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SBK2 SH3 domain binding kinase family member 2 [ Homo sapiens (human) ]

Gene ID: 646643, updated on 25-Nov-2021

Summary

Official Symbol
SBK2provided by HGNC
Official Full Name
SH3 domain binding kinase family member 2provided by HGNC
Primary source
HGNC:HGNC:34416
See related
Ensembl:ENSG00000187550
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SGK069
Expression
Restricted expression toward heart (RPKM 14.0) See more
Orthologs
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Genomic context

See SBK2 in Genome Data Viewer
Location:
19q13.42
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (55528611..55537174, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (56039978..56048500, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase 14 (putative) Neighboring gene scavenger receptor cysteine rich family member with 5 domains Neighboring gene SH3 domain binding kinase family member 3 Neighboring gene zinc finger protein 579

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables MAP kinase kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
serine/threonine-protein kinase SBK2
Names
SH3-binding domain kinase family, member 2
Sugen kinase 69
NP_001357025.1
XP_011525529.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370096.2NP_001357025.1  serine/threonine-protein kinase SBK2

    Status: VALIDATED

    Source sequence(s)
    AC008735
    Consensus CDS
    CCDS42631.1
    Related
    ENSP00000389015.2, ENST00000413299.6
    Conserved Domains (1) summary
    cl21453
    Location:68329
    PKc_like; Protein Kinases, catalytic domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    55528611..55537174 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527227.2XP_011525529.1  serine/threonine-protein kinase SBK2 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:68153
    PKc_like; Protein Kinases, catalytic domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001101401.2: Suppressed sequence

    Description
    NM_001101401.2: This RefSeq was removed because currently there is not sufficient data to support this transcript.
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