Format

Send to:

Choose Destination

LYPD8 LY6/PLAUR domain containing 8 [ Homo sapiens (human) ]

Gene ID: 646627, updated on 18-Aug-2020

Summary

Official Symbol
LYPD8provided by HGNC
Official Full Name
LY6/PLAUR domain containing 8provided by HGNC
Primary source
HGNC:HGNC:44208
See related
Ensembl:ENSG00000259823 MIM:617067
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward colon (RPKM 65.3) See more
Orthologs

Genomic context

See LYPD8 in Genome Data Viewer
Location:
1q44
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (248739415..248755759, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (248902716..248903171, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene LY6/PLAUR domain containing 9, pseudogene Neighboring gene adenosylhomocysteinase pseudogene 8 Neighboring gene uncharacterized LOC107985747 Neighboring gene DPY19L4 pseudogene 1 Neighboring gene SH3 binding domain protein 5 like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

General gene information

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
defense response to Gram-negative bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
defense response to Gram-negative bacterium ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
extracellular region TAS
Traceable Author Statement
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
ly6/PLAUR domain-containing protein 8
Names
phospholipase inhibitor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085474.2NP_001078943.2  ly6/PLAUR domain-containing protein 8 preproprotein

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AEKP01210869, CR589904, FP476111, FP885904
    Consensus CDS
    CCDS73059.1
    Related
    ENSP00000466070.2, ENST00000590317.4
  2. NM_001291283.2NP_001278212.2  ly6/PLAUR domain-containing protein 8 preproprotein

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    CR589904, FP476111, FP885904
    Consensus CDS
    CCDS73059.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    248739415..248755759 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center