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MAGEB17 MAGE family member B17 [ Homo sapiens (human) ]

Gene ID: 645864, updated on 2-Nov-2024

Summary

Official Symbol
MAGEB17provided by HGNC
Official Full Name
MAGE family member B17provided by HGNC
Primary source
HGNC:HGNC:17418
See related
Ensembl:ENSG00000182798 MIM:300763; AllianceGenome:HGNC:17418
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See MAGEB17 in Genome Data Viewer
Location:
Xp22.2
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (16167481..16171464)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (15750384..15754369)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (16185604..16189587)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chrX:15961157-15961364 Neighboring gene SET pseudogene 15 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:16060812-16061354 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:16065714-16066214 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chrX:16094875-16095376 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29452 Neighboring gene Sharpr-MPRA regulatory region 9466 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20677 Neighboring gene MAGEB17 antisense RNA 1 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chrX:16178523-16179722 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:16186339-16187224 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chrX:16197237-16197862 Neighboring gene gastrin releasing peptide receptor Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chrX:16203427-16204626 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:16204620-16205364 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chrX:16233634-16234454 Neighboring gene ribosomal protein L6 pseudogene 30 Neighboring gene uncharacterized LOC124905249 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29453 Neighboring gene H3K27ac hESC enhancer GRCh37_chrX:16464669-16465194 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chrX:16465195-16465720

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
melanoma-associated antigen B17
Names
melanoma antigen family B, 17 (pseudogene)
melanoma antigen family B17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277307.2NP_001264236.1  melanoma-associated antigen B17

    See identical proteins and their annotated locations for NP_001264236.1

    Status: VALIDATED

    Source sequence(s)
    AC078993, DV080535
    Consensus CDS
    CCDS59524.1
    UniProtKB/Swiss-Prot
    A6NE98, A8MXT2
    Related
    ENSP00000382884.2, ENST00000400004.6
    Conserved Domains (2) summary
    pfam01454
    Location:116284
    MAGE; MAGE family
    pfam12440
    Location:591
    MAGE_N; Melanoma associated antigen family N terminal

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    16167481..16171464
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047442355.1XP_047298311.1  melanoma-associated antigen B17 isoform X1

    UniProtKB/Swiss-Prot
    A6NE98, A8MXT2
    Related
    ENSP00000382883.1, ENST00000400003.1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    15750384..15754369
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054327575.1XP_054183550.1  melanoma-associated antigen B17 isoform X1

    UniProtKB/Swiss-Prot
    A6NE98, A8MXT2