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MT1HL1 metallothionein 1H like 1 [ Homo sapiens (human) ]

Gene ID: 645745, updated on 2-Mar-2021

Summary

Official Symbol
MT1HL1provided by HGNC
Official Full Name
metallothionein 1H like 1provided by HGNC
Primary source
HGNC:HGNC:31864
See related
Ensembl:ENSG00000244020
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MT1P2
Summary
This gene is a retrotransposed gene, compared to MT1H (GeneID:4496). This retrogene is transcribed. It retains a full-length CDS, and is assumed to be translated. Compared to the MT1H product, this protein product differs at three internal amino acids, two of which are at metal-binding sites. [provided by RefSeq, Mar 2013]
Orthologs
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Genomic context

See MT1HL1 in Genome Data Viewer
Location:
1q43
Exon count:
1
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (237004103..237004441, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (237167403..237167741, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985368 Neighboring gene VISTA enhancer hs2137 Neighboring gene VISTA enhancer hs2138 Neighboring gene ribosomal protein L35 pseudogene 1 Neighboring gene ryanodine receptor 2 Neighboring gene RN7SK pseudogene 195

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
metal ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cellular response to cadmium ion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to copper ion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to zinc ion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular zinc ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
detoxification of copper ion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
metallothionein 1H-like protein 1
Names
MT-1H-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001276687.2NP_001263616.1  metallothionein 1H-like protein 1

    See identical proteins and their annotated locations for NP_001263616.1

    Status: VALIDATED

    Source sequence(s)
    AF333388, AL359259
    Consensus CDS
    CCDS31068.1
    UniProtKB/Swiss-Prot
    P0DM35
    Related
    ENSP00000476141.1, ENST00000464121.3
    Conserved Domains (1) summary
    pfam00131
    Location:561
    Metallothio; Metallothionein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    237004103..237004441 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_007037.2: Suppressed sequence

    Description
    NG_007037.2: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein and is not a pseudogene.
  2. NM_001039954.2: Suppressed sequence

    Description
    NM_001039954.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
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