Format

Send to:

Choose Destination

Vax2 ventral anterior homeobox 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 64572, updated on 5-Jun-2021

Summary

Official Symbol
Vax2provided by RGD
Official Full Name
ventral anterior homeobox 2provided by RGD
Primary source
RGD:621133
See related
Ensembl:ENSRNOG00000013261
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
mouse homolog is a transcription factor involved in development of the ventral optic vesicle [RGD, Feb 2006]
Expression
Biased expression in Brain (RPKM 2.2), Liver (RPKM 2.2) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Vax2 in Genome Data Viewer
Location:
4q34
Exon count:
3
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (116195576..116219597)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (115388839..115412515)

Chromosome 4 - NC_051339.1Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase-like Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene uncharacterized LOC108350721 Neighboring gene ATPase H+ transporting V1 subunit B1 Neighboring gene ankyrin repeat domain 53

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in axonogenesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within axonogenesis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within camera-type eye development ISO
Inferred from Sequence Orthology
more info
 
involved_in central nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in dorsal/ventral axis specification IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within dorsal/ventral axis specification ISO
Inferred from Sequence Orthology
more info
 
involved_in embryonic eye morphogenesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within embryonic eye morphogenesis ISO
Inferred from Sequence Orthology
more info
 
involved_in forebrain development IEA
Inferred from Electronic Annotation
more info
 
involved_in forebrain development ISO
Inferred from Sequence Orthology
more info
 
involved_in forebrain development ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
involved_in neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in retina development in camera-type eye IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within retina development in camera-type eye ISO
Inferred from Sequence Orthology
more info
 
involved_in visual perception IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ventral anterior homeobox 2
Names
ventral anterior homeobox containing gene 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022637.1NP_072159.1  ventral anterior homeobox 2

    See identical proteins and their annotated locations for NP_072159.1

    Status: PROVISIONAL

    Source sequence(s)
    AF113516
    UniProtKB/Swiss-Prot
    Q9JLZ9
    Related
    ENSRNOP00000018128.1, ENSRNOT00000018128.2
    Conserved Domains (1) summary
    pfam00046
    Location:105158
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051339.1 Reference mRatBN7.2 Primary Assembly

    Range
    116195576..116219597
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039108321.1XP_038964249.1  ventral anterior homeobox 2 isoform X1

    Conserved Domains (1) summary
    pfam00046
    Location:241
    Homeobox; Homeobox domain
Support Center