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PRAMEF19 PRAME family member 19 [ Homo sapiens (human) ]

Gene ID: 645414, updated on 26-Oct-2022

Summary

Official Symbol
PRAMEF19provided by HGNC
Official Full Name
PRAME family member 19provided by HGNC
Primary source
HGNC:HGNC:24908
See related
Ensembl:ENSG00000204480 AllianceGenome:HGNC:24908
Gene type
protein coding
RefSeq status
INFERRED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of transcription, DNA-templated; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See PRAMEF19 in Genome Data Viewer
Location:
1p36.21
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (13368431..13371947, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (12809705..12813221, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (13694889..13698405, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene PRAME family member 15 Neighboring gene PRAME family member 14 Neighboring gene PRAME family member 17 Neighboring gene PRAME family member 20

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
PRAME family member 19
Names
PRAME family member-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099790.5NP_001093260.3  PRAME family member 19

    Status: INFERRED

    Source sequence(s)
    AC243961
    Consensus CDS
    CCDS41263.1
    UniProtKB/Swiss-Prot
    Q5SWL8
    Related
    ENSP00000365269.2, ENST00000376101.4

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    13368431..13371947 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    12809705..12813221 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_005160.3: Suppressed sequence

    Description
    NG_005160.3: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.