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TEKT3 tektin 3 [ Homo sapiens (human) ]

Gene ID: 64518, updated on 15-Jun-2019

Summary

Official Symbol
TEKT3provided by HGNC
Official Full Name
tektin 3provided by HGNC
Primary source
HGNC:HGNC:14293
See related
Ensembl:ENSG00000125409 MIM:612683
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward testis (RPKM 5.3) See more
Orthologs

Genomic context

See TEKT3 in Genome Data Viewer
Location:
17p12
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 17 NC_000017.11 (15303811..15343682, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (15207129..15244958, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371547 Neighboring gene peripheral myelin protein 22 Neighboring gene microRNA 4731 Neighboring gene RNA, U6 small nuclear 799, pseudogene Neighboring gene RNA, 7SL, cytoplasmic 792, pseudogene Neighboring gene TVP23C-CDRT4 readthrough Neighboring gene CMT1A duplicated region transcript 4 Neighboring gene ribosomal protein L9 pseudogene 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32828

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
flagellated sperm motility ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of brood size ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
acrosomal membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
extracellular exosome HDA PubMed 
microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus HDA PubMed 
outer acrosomal membrane IEA
Inferred from Electronic Annotation
more info
 
sperm flagellum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sperm flagellum ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
tektin-3
Names
testicular microtubules-related protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031898.3NP_114104.1  tektin-3

    See identical proteins and their annotated locations for NP_114104.1

    Status: REVIEWED

    Source sequence(s)
    AF334676, BC031688
    Consensus CDS
    CCDS11169.1
    UniProtKB/Swiss-Prot
    Q9BXF9
    Related
    ENSP00000379263.1, ENST00000395930.6
    Conserved Domains (1) summary
    pfam03148
    Location:99478
    Tektin; Tektin family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    15303811..15343682 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017024954.1XP_016880443.1  tektin-3 isoform X1

    UniProtKB/Swiss-Prot
    Q9BXF9
    Conserved Domains (1) summary
    pfam03148
    Location:99478
    Tektin; Tektin family
  2. XM_011523990.2XP_011522292.1  tektin-3 isoform X2

    Conserved Domains (1) summary
    pfam03148
    Location:1312
    Tektin; Tektin family
  3. XM_017024955.1XP_016880444.1  tektin-3 isoform X2

    Conserved Domains (1) summary
    pfam03148
    Location:1312
    Tektin; Tektin family
  4. XM_011523989.1XP_011522291.1  tektin-3 isoform X1

    See identical proteins and their annotated locations for XP_011522291.1

    UniProtKB/Swiss-Prot
    Q9BXF9
    Related
    ENSP00000343995.2, ENST00000338696.6
    Conserved Domains (1) summary
    pfam03148
    Location:99478
    Tektin; Tektin family
  5. XM_011523988.2XP_011522290.1  tektin-3 isoform X1

    See identical proteins and their annotated locations for XP_011522290.1

    UniProtKB/Swiss-Prot
    Q9BXF9
    Conserved Domains (1) summary
    pfam03148
    Location:99478
    Tektin; Tektin family
  6. XM_017024956.1XP_016880445.1  tektin-3 isoform X3

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