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MEIG1 meiosis/spermiogenesis associated 1 [ Homo sapiens (human) ]

Gene ID: 644890, updated on 18-Sep-2022

Summary

Official Symbol
MEIG1provided by HGNC
Official Full Name
meiosis/spermiogenesis associated 1provided by HGNC
Primary source
HGNC:HGNC:23429
See related
Ensembl:ENSG00000197889 MIM:614174; AllianceGenome:HGNC:23429
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SPATA39; bA2K17.3
Summary
Predicted to act upstream of or within cellular protein localization; manchette assembly; and sperm axoneme assembly. Predicted to be located in cytosol and manchette. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 4.2) and brain (RPKM 0.2) See more
Orthologs
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Genomic context

See MEIG1 in Genome Data Viewer
Location:
10p13
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (14954228..14988050)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (14973346..15002020)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (15001387..15030049)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene heat shock protein family A (Hsp70) member 14 Neighboring gene uncharacterized LOC124902382 Neighboring gene SUV39H2 histone lysine methyltransferase Neighboring gene DNA cross-link repair 1C Neighboring gene olfactory receptor family 7 subfamily E member 110 pseudogene Neighboring gene olfactory receptor family 7 subfamily E member 26 pseudogene Neighboring gene olfactory receptor family 7 subfamily E member 115 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in manchette assembly IEA
Inferred from Electronic Annotation
more info
 
involved_in protein localization IEA
Inferred from Electronic Annotation
more info
 
involved_in sperm axoneme assembly IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in manchette IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
meiosis expressed gene 1 protein homolog
Names
meiosis expressed gene 1 homolog
spermatogenesis associated 39

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080836.3NP_001074305.1  meiosis expressed gene 1 protein homolog

    See identical proteins and their annotated locations for NP_001074305.1

    Status: VALIDATED

    Source sequence(s)
    AA971146, AI694434, AL360083, BG189536
    Consensus CDS
    CCDS31151.1
    UniProtKB/Swiss-Prot
    Q5JSS6
    Related
    ENSP00000384334.1, ENST00000407572.6
    Conserved Domains (1) summary
    pfam15163
    Location:1186
    Meiosis_expr; Meiosis-expressed

RNA

  1. NR_147060.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL360083, BG189096, BX115809

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    14954228..14988050
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024448136.1XP_024303904.1  meiosis expressed gene 1 protein homolog isoform X1

    Conserved Domains (1) summary
    pfam15163
    Location:42117
    Meiosis_expr; Meiosis-expressed
  2. XM_047425662.1XP_047281618.1  meiosis expressed gene 1 protein homolog isoform X2

    UniProtKB/Swiss-Prot
    Q5JSS6
    Related
    ENSP00000367486.1, ENST00000378240.1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    14973346..15002020
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_134493.1: Suppressed sequence

    Description
    NR_134493.1: This RefSeq was removed because currently there is insufficient support for the transcript.