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Zfp280b zinc finger protein 280B [ Mus musculus (house mouse) ]

Gene ID: 64453, updated on 5-Mar-2024

Summary

Official Symbol
Zfp280bprovided by MGI
Official Full Name
zinc finger protein 280Bprovided by MGI
Primary source
MGI:MGI:1927865
See related
Ensembl:ENSMUSG00000049764 AllianceGenome:MGI:1927865
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Suhw2; D10Jhu82e
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZNF280B (zinc finger protein 280B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 9.7), ovary adult (RPKM 7.3) and 28 other tissues See more
Orthologs
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Genomic context

See Zfp280b in Genome Data Viewer
Location:
10 C1; 10 38.67 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (75868235..75878804)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (76032401..76042970)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40698 Neighboring gene predicted gene 5134 Neighboring gene STARR-seq mESC enhancer starr_27167 Neighboring gene STARR-positive B cell enhancer ABC_E8345 Neighboring gene STARR-seq mESC enhancer starr_27168 Neighboring gene microRNA 6409 Neighboring gene STARR-seq mESC enhancer starr_27169 Neighboring gene STARR-positive B cell enhancer ABC_E3892 Neighboring gene STARR-seq mESC enhancer starr_27170 Neighboring gene STARR-seq mESC enhancer starr_27172 Neighboring gene solute carrier family 5 (neutral amino acid transporters, system A), member 4b Neighboring gene predicted gene 16222 Neighboring gene STARR-seq mESC enhancer starr_27174 Neighboring gene solute carrier family 5 (neutral amino acid transporters, system A), member 4b pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General protein information

Preferred Names
zinc finger protein 280b
Names
suppressor of hairy wing homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177475.3NP_803426.2  zinc finger protein 280b

    See identical proteins and their annotated locations for NP_803426.2

    Status: VALIDATED

    Source sequence(s)
    AC134382, AK079824, BC094574
    Consensus CDS
    CCDS23942.1
    UniProtKB/TrEMBL
    Q3UMQ7, Q505F4
    Related
    ENSMUSP00000056340.7, ENSMUST00000061617.7
    Conserved Domains (2) summary
    sd00017
    Location:336357
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:53221
    DUF4195; Domain of unknown function (DUF4195)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    75868235..75878804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036155940.1XP_036011833.1  zinc finger protein 280b isoform X1

    UniProtKB/TrEMBL
    Q3UMQ7, Q505F4
    Conserved Domains (2) summary
    sd00017
    Location:336357
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:53221
    DUF4195; Domain of unknown function (DUF4195)
  2. XM_006513942.2XP_006514005.1  zinc finger protein 280b isoform X1

    See identical proteins and their annotated locations for XP_006514005.1

    UniProtKB/TrEMBL
    Q3UMQ7, Q505F4
    Conserved Domains (2) summary
    sd00017
    Location:336357
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:53221
    DUF4195; Domain of unknown function (DUF4195)
  3. XM_006513943.2XP_006514006.1  zinc finger protein 280b isoform X1

    See identical proteins and their annotated locations for XP_006514006.1

    UniProtKB/TrEMBL
    Q3UMQ7, Q505F4
    Conserved Domains (2) summary
    sd00017
    Location:336357
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13836
    Location:53221
    DUF4195; Domain of unknown function (DUF4195)