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ZCCHC18 zinc finger CCHC-type containing 18 [ Homo sapiens (human) ]

Gene ID: 644353, updated on 25-Jan-2022

Summary

Official Symbol
ZCCHC18provided by HGNC
Official Full Name
zinc finger CCHC-type containing 18provided by HGNC
Primary source
HGNC:HGNC:32459
See related
Ensembl:ENSG00000166707 AllianceGenome:HGNC:32459
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SIZN2; PNMA7B
Summary
Predicted to enable metal ion binding activity. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Ubiquitous expression in ovary (RPKM 1.7), brain (RPKM 1.6) and 25 other tissues See more
Orthologs
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Genomic context

See ZCCHC18 in Genome Data Viewer
Location:
Xq22.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (104112445..104121330)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (103357214..103360533)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene thymosin beta 15B-like Neighboring gene developmental pluripotency associated 3 pseudogene Neighboring gene solute carrier family 25 member 53 Neighboring gene uncharacterized LOC286437 Neighboring gene family with sequence similarity 199, X-linked

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger CCHC domain-containing protein 18
Names
paraneoplastic Ma antigen family member 7B
putative zinc finger CCHC domain-containing protein 18
zinc finger, CCHC domain containing 12 pseudogene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001143978.3NP_001137450.1  zinc finger CCHC domain-containing protein 18

    See identical proteins and their annotated locations for NP_001137450.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the supported protein.
    Source sequence(s)
    AC234783, AI656548, DA781887, DA790216, DA808943
    Consensus CDS
    CCDS65304.1
    UniProtKB/Swiss-Prot
    P0CG32
    Related
    ENSP00000498828.1, ENST00000650639.1
    Conserved Domains (1) summary
    pfam14893
    Location:1212
    PNMA; PNMA

RNA

  1. NR_026694.3 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate internal segment, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AC234783, AI656548, CN272796, DA808943
    Related
    ENST00000422784.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    104112445..104121330
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011531012.3XP_011529314.1  zinc finger CCHC domain-containing protein 18 isoform X1

    See identical proteins and their annotated locations for XP_011529314.1

    UniProtKB/Swiss-Prot
    P0CG32
    Conserved Domains (1) summary
    pfam14893
    Location:1212
    PNMA; PNMA
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