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ACTR6 actin related protein 6 [ Homo sapiens (human) ]

Gene ID: 64431, updated on 13-Mar-2020

Summary

Official Symbol
ACTR6provided by HGNC
Official Full Name
actin related protein 6provided by HGNC
Primary source
HGNC:HGNC:24025
See related
Ensembl:ENSG00000075089
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ARP6; CDA12; hARP6; hARPX; HSPC281; MSTP136
Expression
Ubiquitous expression in brain (RPKM 10.9), testis (RPKM 9.8) and 25 other tissues See more
Orthologs

Genomic context

See ACTR6 in Genome Data Viewer
Location:
12q23.1
Exon count:
11
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (100200087..100224424)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (100593865..100618202)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene RNA, 7SL, cytoplasmic 176, pseudogene Neighboring gene GOLGA2 pseudogene 5 Neighboring gene Sharpr-MPRA regulatory region 7946 Neighboring gene microRNA 1827 Neighboring gene DEP domain containing 4 Neighboring gene SCY1 like pseudokinase 2 Neighboring gene solute carrier family 17 member 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13433

Gene Ontology Provided by GOA

Function Evidence Code Pubs
nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
histone exchange IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Swr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
actin-related protein 6
Names
ARP6 actin related protein 6 homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022496.4NP_071941.1  actin-related protein 6

    See identical proteins and their annotated locations for NP_071941.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes a protein of 396aa.
    Source sequence(s)
    AB038229, AK124075
    Consensus CDS
    CCDS9074.1
    UniProtKB/Swiss-Prot
    Q9GZN1
    Related
    ENSP00000188312.2, ENST00000188312.6
    Conserved Domains (1) summary
    smart00268
    Location:2394
    ACTIN; Actin

RNA

  1. NR_048568.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate splice site at the 5' exon, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region and is likely a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC050679, DB022992
    Related
    ENST00000546902.5
  2. NR_048569.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has an alternate splice site in the 5' region, compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region and is likely a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AB038229, AK023684, DB022992
    Related
    ENST00000548180.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    100200087..100224424
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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