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PCNX4 pecanex 4 [ Homo sapiens (human) ]

Gene ID: 64430, updated on 23-Nov-2021

Summary

Official Symbol
PCNX4provided by HGNC
Official Full Name
pecanex 4provided by HGNC
Primary source
HGNC:HGNC:20349
See related
Ensembl:ENSG00000126773
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FBP2; PCNXL4; C14orf135
Expression
Ubiquitous expression in prostate (RPKM 4.7), endometrium (RPKM 4.5) and 25 other tissues See more
Orthologs
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Genomic context

See PCNX4 in Genome Data Viewer
Location:
14q23.1
Exon count:
12
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (60091911..60148221)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (60558629..60614939)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene reticulon 1 Neighboring gene microRNA 5586 Neighboring gene leucine rich repeat containing 9 Neighboring gene PCNX4 divergent transcript Neighboring gene Sharpr-MPRA regulatory region 1153 Neighboring gene dehydrogenase/reductase 7 Neighboring gene short coiled-coil protein pseudogene 1 Neighboring gene proteasome subunit alpha 3 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ12799, FLJ38170

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
pecanex-like protein 4
Names
HCV F protein-binding protein 2
HCV F-interacting protein
hepatitis C virus F protein-binding protein 2
pecanex homolog 4
pecanex homolog protein 4
pecanex-like 4
pecanex-like protein C14orf135

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330177.2NP_001317106.1  pecanex-like protein 4 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AA651916, AL157911, AL163853
    Consensus CDS
    CCDS81809.1
    UniProtKB/Swiss-Prot
    Q63HM2
    Related
    ENSP00000384801.1, ENST00000406854.6
  2. NM_022495.5NP_071940.4  pecanex-like protein 4 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate exon in the 5' coding region, resulting in the use of a downstream start codon compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.
    Source sequence(s)
    AA651916, AK095489, AL157911, BC033843
    Consensus CDS
    CCDS32091.2
    UniProtKB/Swiss-Prot
    Q63HM2
    UniProtKB/TrEMBL
    B6ZDM2
    Related
    ENSP00000317396.4, ENST00000317623.8
    Conserved Domains (1) summary
    pfam05041
    Location:831930
    Pecanex_C; Pecanex protein (C-terminus)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    60091911..60148221
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_943509.3 RNA Sequence

  2. XR_943508.3 RNA Sequence

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