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WIPF3 WAS/WASL interacting protein family member 3 [ Homo sapiens (human) ]

Gene ID: 644150, updated on 25-Nov-2021

Summary

Official Symbol
WIPF3provided by HGNC
Official Full Name
WAS/WASL interacting protein family member 3provided by HGNC
Primary source
HGNC:HGNC:22004
See related
Ensembl:ENSG00000122574 MIM:612432
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CR16
Expression
Biased expression in ovary (RPKM 20.0), testis (RPKM 14.2) and 10 other tissues See more
Orthologs
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Genomic context

See WIPF3 in Genome Data Viewer
Location:
7p14.3
Exon count:
10
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (29806508..29917065)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (29846124..29956677)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene DPY19L2 pseudogene 3 Neighboring gene zinc and ring finger 2 pseudogene 2 Neighboring gene CRISPRi-validated cis-regulatory element chr7.1421 Neighboring gene secernin 1 Neighboring gene FKBP14 antisense RNA 1 Neighboring gene FKBP prolyl isomerase 14

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

Associated conditions

Description Tests
Genetic variants near PDGFRA are associated with corneal curvature in Australians.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ36931

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in actin filament-based movement IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 
involved_in spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in actin filament IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
WAS/WASL-interacting protein family member 3
Names
corticosteroids and regional expression protein 16 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080529.3NP_001073998.2  WAS/WASL-interacting protein family member 3 isoform 1

    See identical proteins and their annotated locations for NP_001073998.2

    Status: VALIDATED

    Source sequence(s)
    AC004912, AW105171, BX107905
    Consensus CDS
    CCDS56472.1
    UniProtKB/Swiss-Prot
    A6NGB9
    Related
    ENSP00000242140.6, ENST00000242140.9
    Conserved Domains (1) summary
    pfam02205
    Location:4269
    WH2; WH2 motif
  2. NM_001391973.1NP_001378902.1  WAS/WASL-interacting protein family member 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC004912
    Related
    ENSP00000386790.1, ENST00000409123.5
    Conserved Domains (1) summary
    cd22077
    Location:4271
    WH2_WAS_WASL-2_3; Wiskott Aldrich syndrome homology region 2 (WH2 motif) in WAS/WASL-interacting protein (WIP) family members 2 and 3

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    29806508..29917065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017012522.1XP_016868011.1  WAS/WASL-interacting protein family member 3 isoform X1

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