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EXOC1L exocyst complex component 1 like [ Homo sapiens (human) ]

Gene ID: 644145, updated on 5-Aug-2022

Summary

Official Symbol
EXOC1Lprovided by HGNC
Official Full Name
exocyst complex component 1 likeprovided by HGNC
Primary source
HGNC:HGNC:53433
See related
Ensembl:ENSG00000250821 AllianceGenome:HGNC:53433
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in Golgi to plasma membrane transport and exocytosis. Predicted to be part of exocyst. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See EXOC1L in Genome Data Viewer
Location:
4q12
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (55819790..55837489)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (59307935..59325634)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (56685956..56703655)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 7030 Neighboring gene RNA, U6 small nuclear 276, pseudogene Neighboring gene uncharacterized LOC105377661 Neighboring gene exocyst complex component 1 Neighboring gene uncharacterized LOC105377663 Neighboring gene RNA, U6 small nuclear 652, pseudogene

Genomic regions, transcripts, and products

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables phosphatidylinositol-4,5-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in Golgi to plasma membrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
part_of exocyst IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
exocyst complex component 1-like
Names
exocyst -like pseudogene
exocyst complex component 1 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001351574.3NP_001338503.1  exocyst complex component 1-like isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC110611
    Consensus CDS
    CCDS87223.1
    UniProtKB/Swiss-Prot
    A0A1B0GW35
    Related
    ENSP00000490760.1, ENST00000636125.2
    Conserved Domains (1) summary
    cd14682
    Location:2119
    PH-EXOC1_like; PH-like domain of Exocyst complex component 1-like
  2. NM_001351575.3NP_001338504.1  exocyst complex component 1-like isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC110611
    Conserved Domains (1) summary
    cl17171
    Location:169
    PH-like; Pleckstrin homology-like domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    55819790..55837489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024454185.2XP_024309953.1  exocyst complex component 1-like isoform X1

    Conserved Domains (1) summary
    cl17171
    Location:169
    PH-like; Pleckstrin homology-like domain

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    59307935..59325634
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)