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CDH24 cadherin 24 [ Homo sapiens (human) ]

Gene ID: 64403, updated on 8-Jul-2021

Summary

Official Symbol
CDH24provided by HGNC
Official Full Name
cadherin 24provided by HGNC
Primary source
HGNC:HGNC:14265
See related
Ensembl:ENSG00000139880 MIM:618599
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CDH11L
Expression
Ubiquitous expression in endometrium (RPKM 4.3), gall bladder (RPKM 3.2) and 23 other tissues See more
Orthologs
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Genomic context

See CDH24 in Genome Data Viewer
Location:
14q11.2
Exon count:
14
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (23047067..23057619, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (23516276..23526729, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene proteasome 20S subunit beta 5 Neighboring gene Sharpr-MPRA regulatory region 11879 Neighboring gene proteasome subunit beta 11 Neighboring gene collagen alpha-2(I) chain-like Neighboring gene apoptotic chromatin condensation inducer 1 Neighboring gene uncharacterized LOC107984665 Neighboring gene chromosome 14 open reading frame 119 Neighboring gene leishmanolysin like peptidase 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ25193, MGC131880

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables cadherin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of catenin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cell-cell junction IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
cadherin-24
Names
cadherin 24, type 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022478.4NP_071923.2  cadherin-24 isoform 1 precursor

    See identical proteins and their annotated locations for NP_071923.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AY260901, BC009332, DC310509
    Consensus CDS
    CCDS9585.1
    UniProtKB/Swiss-Prot
    Q86UP0
    Related
    ENSP00000380517.3, ENST00000397359.7
    Conserved Domains (4) summary
    cd11304
    Location:154255
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:70148
    CA; Cadherin repeats
    pfam01049
    Location:671812
    Cadherin_C; Cadherin cytoplasmic region
    cl09101
    Location:521615
    E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus
  2. NM_144985.4NP_659422.2  cadherin-24 isoform 2 precursor

    See identical proteins and their annotated locations for NP_659422.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AY260900, AY358199, BC009332, DC310509
    Consensus CDS
    CCDS9586.1
    UniProtKB/Swiss-Prot
    Q86UP0
    Related
    ENSP00000434821.2, ENST00000487137.7
    Conserved Domains (4) summary
    cd11304
    Location:379475
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:70148
    CA; Cadherin repeats
    pfam01049
    Location:633774
    Cadherin_C; Cadherin cytoplasmic region
    cl09101
    Location:483577
    E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    23047067..23057619 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011537089.1XP_011535391.1  cadherin-24 isoform X1

    Conserved Domains (2) summary
    cd11304
    Location:154255
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00112
    Location:70148
    CA; Cadherin repeats
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