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CBWD6 COBW domain containing 6 [ Homo sapiens (human) ]

Gene ID: 644019, updated on 23-Nov-2021

Summary

Official Symbol
CBWD6provided by HGNC
Official Full Name
COBW domain containing 6provided by HGNC
Primary source
HGNC:HGNC:31978
See related
Ensembl:ENSG00000215126
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CBWD7
Annotation information
Annotation category: suggests misassembly
Expression
Ubiquitous expression in kidney (RPKM 11.5), thyroid (RPKM 10.9) and 25 other tissues See more
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Genomic context

See CBWD6 in Genome Data Viewer
Location:
9p11.2
Exon count:
23
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (41131309..41198865, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (69204538..69262546, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC440896 Neighboring gene forkhead box D4 like 6 Neighboring gene uncharacterized LOC107986998 Neighboring gene protein FRG1B-like Neighboring gene microRNA 4477a

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ40320, FLJ60409, DKFZp686L07117

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
COBW domain-containing protein 6
Names
COBW domain containing 7
cobalamin synthase W domain-containing protein 6
cobalamin synthetase W domain-containing protein 6
putative COBW domain-containing protein 7
putative cobalamin synthase W domain-containing protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085457.2NP_001078926.1  COBW domain-containing protein 6 isoform 1

    See identical proteins and their annotated locations for NP_001078926.1

    Status: VALIDATED

    Source sequence(s)
    BX255923
    Consensus CDS
    CCDS43827.1
    UniProtKB/Swiss-Prot
    Q4V339
    Related
    ENSP00000366608.4, ENST00000377391.8
    Conserved Domains (3) summary
    COG0523
    Location:42376
    YejR; GTPase, G3E family [General function prediction only]
    pfam07683
    Location:274373
    CobW_C; Cobalamin synthesis protein cobW C-terminal domain
    cl21455
    Location:43207
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. NM_001386876.1NP_001373805.1  COBW domain-containing protein 6 isoform 2

    Status: VALIDATED

    Source sequence(s)
    BX255923
    Conserved Domains (3) summary
    COG3044
    Location:1962
    COG3044; Predicted ATPase of the ABC class [General function prediction only]
    cd03112
    Location:43226
    CobW-like; cobalamin synthesis protein CobW
    pfam07683
    Location:254353
    CobW_C; Cobalamin synthesis protein cobW C-terminal domain
  3. NM_001386877.1NP_001373806.1  COBW domain-containing protein 6 isoform 3

    Status: VALIDATED

    Source sequence(s)
    BX255923
    Conserved Domains (2) summary
    COG0523
    Location:42327
    YejR; GTPase, G3E family [General function prediction only]
    COG3044
    Location:1962
    COG3044; Predicted ATPase of the ABC class [General function prediction only]

RNA

  1. NR_170339.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    BX255923
    Related
    ENST00000494538.6

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    41131309..41198865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017015028.1XP_016870517.1  COBW domain-containing protein 6 isoform X10

  2. XM_017015025.1XP_016870514.1  COBW domain-containing protein 6 isoform X7

  3. XM_017015022.1XP_016870511.1  COBW domain-containing protein 6 isoform X4

  4. XM_017015023.1XP_016870512.1  COBW domain-containing protein 6 isoform X5

  5. XM_017015021.1XP_016870510.1  COBW domain-containing protein 6 isoform X3

  6. XM_017015026.1XP_016870515.1  COBW domain-containing protein 6 isoform X8

  7. XM_017015019.1XP_016870508.1  COBW domain-containing protein 6 isoform X1

  8. XM_017015036.1XP_016870525.1  COBW domain-containing protein 6 isoform X20

  9. XM_024447653.1XP_024303421.1  COBW domain-containing protein 6 isoform X19

    Conserved Domains (2) summary
    COG0523
    Location:42347
    YejR; GTPase, G3E family [General function prediction only]
    cl26601
    Location:1962
    ABC_ATPase; Predicted ATPase of the ABC class
  10. XM_017015035.1XP_016870524.1  COBW domain-containing protein 6 isoform X18

    UniProtKB/TrEMBL
    H0Y5V3
    Related
    ENSP00000401079.2, ENST00000456520.5
  11. XM_017015029.2XP_016870518.1  COBW domain-containing protein 6 isoform X11

  12. XM_017015034.1XP_016870523.1  COBW domain-containing protein 6 isoform X17

  13. XM_017015033.1XP_016870522.1  COBW domain-containing protein 6 isoform X16

  14. XM_024447652.1XP_024303420.1  COBW domain-containing protein 6 isoform X14

    Conserved Domains (1) summary
    cl26870
    Location:20208
    CobW_C; Cobalamin synthesis protein cobW C-terminal domain
  15. XM_017015031.1XP_016870520.1  COBW domain-containing protein 6 isoform X13

  16. XM_017015030.1XP_016870519.1  COBW domain-containing protein 6 isoform X12

  17. XM_017015027.1XP_016870516.1  COBW domain-containing protein 6 isoform X9

  18. XM_017015032.1XP_016870521.1  COBW domain-containing protein 6 isoform X15

RNA

  1. XR_001746360.1 RNA Sequence

  2. XR_001746362.1 RNA Sequence

  3. XR_001746359.1 RNA Sequence

  4. XR_001746361.1 RNA Sequence

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