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Pllp plasmolipin [ Rattus norvegicus (Norway rat) ]

Gene ID: 64364, updated on 30-Sep-2021

Summary

Official Symbol
Pllpprovided by RGD
Official Full Name
plasmolipinprovided by RGD
Primary source
RGD:621478
See related
EnsemblRapid:ENSRNOG00000016558
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Tm4sf11
Summary
induces the formation of voltage dependent K+ selective ion channels in lipid bilayers; may play a role in myelination [RGD, Feb 2006]
Expression
Biased expression in Kidney (RPKM 338.9), Brain (RPKM 188.8) and 6 other tissues See more
Orthologs
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Genomic context

See Pllp in Genome Data Viewer
Location:
19p13
Exon count:
4
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (10315104..10335892)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (10731855..10752641)

Chromosome 19 - NC_051354.1Genomic Context describing neighboring genes Neighboring gene transfer RNA leucine (anticodon CAG) Neighboring gene transfer RNA leucine (anticodon CAG) Neighboring gene ADP-ribosylation factor like GTPase 2 binding protein Neighboring gene ring finger and SPRY domain containing 1 Neighboring gene proteasome activator subunit 3 interacting protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables structural constituent of myelin sheath IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in ion transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in myelination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in myelination IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in response to wounding IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in compact myelin IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane raft IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
plasmolipin
Names
plasma membrane proteolipid (plasmolipin)
transmembrane 4 superfamily member 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022533.2NP_071978.1  plasmolipin

    See identical proteins and their annotated locations for NP_071978.1

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000303
    UniProtKB/Swiss-Prot
    P47987
    Related
    ENSRNOP00000022277.2, ENSRNOT00000022277.4
    Conserved Domains (1) summary
    pfam01284
    Location:50160
    MARVEL; Membrane-associating domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051354.1 Reference mRatBN7.2 Primary Assembly

    Range
    10315104..10335892
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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