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RNF224 ring finger protein 224 [ Homo sapiens (human) ]

Gene ID: 643596, updated on 13-May-2022

Summary

Official Symbol
RNF224provided by HGNC
Official Full Name
ring finger protein 224provided by HGNC
Primary source
HGNC:HGNC:41912
See related
Ensembl:ENSG00000233198 AllianceGenome:HGNC:41912
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable metal ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See RNF224 in Genome Data Viewer
Location:
9q34.3
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (137227502..137229640)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (149465171..149467309)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (140121954..140124092)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene ring finger protein 208 Neighboring gene hESC enhancers GRCh37_chr9:140121623-140122123 and GRCh37_chr9:140122257-140122882 Neighboring gene cysteine rich tail 1 Neighboring gene solute carrier family 34 member 3 Neighboring gene tubulin beta 4B class IVb Neighboring gene family with sequence similarity 166 member A

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190228.2NP_001177157.1  RING finger protein 224

    See identical proteins and their annotated locations for NP_001177157.1

    Status: VALIDATED

    Source sequence(s)
    BX255925
    Consensus CDS
    CCDS55356.1
    UniProtKB/Swiss-Prot
    P0DH78
    Related
    ENSP00000406665.3, ENST00000445101.4
    Conserved Domains (1) summary
    cd00162
    Location:2374
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    137227502..137229640
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    149465171..149467309
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)