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Gng13 guanine nucleotide binding protein (G protein), gamma 13 [ Mus musculus (house mouse) ]

Gene ID: 64337, updated on 18-Sep-2024

Summary

Official Symbol
Gng13provided by MGI
Official Full Name
guanine nucleotide binding protein (G protein), gamma 13provided by MGI
Primary source
MGI:MGI:1925616
See related
Ensembl:ENSMUSG00000025739 AllianceGenome:MGI:1925616
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hg3j; Ggamma13; 1500031D04Rik
Summary
Predicted to enable G-protein beta-subunit binding activity. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway and sensory perception of taste. Located in dendrite. Part of heterotrimeric G-protein complex. Is expressed in brain; gonad; gut; and liver. Orthologous to human GNG13 (G protein subunit gamma 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in cerebellum adult (RPKM 73.0), cortex adult (RPKM 33.6) and 1 other tissue See more
Orthologs
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Genomic context

See Gng13 in Genome Data Viewer
Location:
17 A3.3; 17 12.82 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (25936146..25938076)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25717172..25719102)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930541O19 gene Neighboring gene NSA2 ribosome biogenesis homolog pseudogene Neighboring gene CTF18, chromosome transmission fidelity factor 18 Neighboring gene STARR-positive B cell enhancer ABC_E3190 Neighboring gene RNA pseudouridylate synthase domain containing 1 Neighboring gene mesothelin-like

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G-protein beta-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables G-protein beta-subunit binding ISO
Inferred from Sequence Orthology
more info
 
enables G-protein beta-subunit binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in dendrite IDA
Inferred from Direct Assay
more info
PubMed 
part_of heterotrimeric G-protein complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of heterotrimeric G-protein complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in membrane TAS
Traceable Author Statement
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
Names
heterotrimeric guanine nucleotide-binding protein 3j

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357782.1NP_001344711.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13

    Status: VALIDATED

    Source sequence(s)
    AC134908, EH103048
    Consensus CDS
    CCDS37503.1
    UniProtKB/Swiss-Prot
    Q9JMF3
    Related
    ENSMUSP00000110760.4, ENSMUST00000115108.4
    Conserved Domains (1) summary
    cd00068
    Location:661
    GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors
  2. NM_022422.5NP_071867.1  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13

    See identical proteins and their annotated locations for NP_071867.1

    Status: VALIDATED

    Source sequence(s)
    BU554843, EH103048
    Consensus CDS
    CCDS37503.1
    UniProtKB/Swiss-Prot
    Q9JMF3
    Related
    ENSMUSP00000131648.2, ENSMUST00000172002.8
    Conserved Domains (1) summary
    cd00068
    Location:661
    GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    25936146..25938076
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)