U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ZC3H11B zinc finger CCCH-type containing 11B [ Homo sapiens (human) ]

Gene ID: 643136, updated on 5-Aug-2022

Summary

Official Symbol
ZC3H11Bprovided by HGNC
Official Full Name
zinc finger CCCH-type containing 11Bprovided by HGNC
Primary source
HGNC:HGNC:25659
See related
Ensembl:ENSG00000215817 AllianceGenome:HGNC:25659
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZC3HDC11B
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ZC3H11B in Genome Data Viewer
Location:
1q41
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (219608012..219613105, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (218844272..218849370, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (219781354..219786447, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene LYPLAL1 antisense RNA 1 Neighboring gene uncharacterized LOC124904514 Neighboring gene U2 spliceosomal RNA Neighboring gene Sharpr-MPRA regulatory region 297 Neighboring gene uncharacterized LOC105372926 Neighboring gene RNA, 5S ribosomal pseudogene 76

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

EBI GWAS Catalog

Description
Genetic variants on chromosome 1q41 influence ocular axial length and high myopia.
EBI GWAS Catalog
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.
EBI GWAS Catalog
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in poly(A)+ mRNA export from nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
zinc finger CCCH domain-containing protein 11B
Names
zinc finger CCCH-type domain containing 11B

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355457.3NP_001342386.1  zinc finger CCCH domain-containing protein 11B

    Status: VALIDATED

    Source sequence(s)
    AL356364
    Consensus CDS
    CCDS86051.1
    UniProtKB/Swiss-Prot
    A0A1B0GTU1
    Related
    ENSP00000498875.1, ENST00000651890.2
    Conserved Domains (1) summary
    pfam15663
    Location:1110
    zf-CCCH_3; Zinc-finger containing family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    219608012..219613105 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    218844272..218849370 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_007367.3: Suppressed sequence

    Description
    NG_007367.3: This RefSeq was removed because it is now thought that this locus is a transcribed gene.
  2. NM_001085394.1: Suppressed sequence

    Description
    NM_001085394.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.