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INSYN2A inhibitory synaptic factor 2A [ Homo sapiens (human) ]

Gene ID: 642938, updated on 2-Mar-2021

Summary

Official Symbol
INSYN2Aprovided by HGNC
Official Full Name
inhibitory synaptic factor 2Aprovided by HGNC
Primary source
HGNC:HGNC:33859
See related
Ensembl:ENSG00000188916 MIM:617129
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
INSYN2; FAM196A; C10orf141
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See INSYN2A in Genome Data Viewer
Location:
10q26.2
Exon count:
7
Annotation release Status Assembly Chr Location
109.20210226 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (127135430..127196591, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (128933694..128994855, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene dedicator of cytokinesis 1 Neighboring gene uncharacterized LOC107984059 Neighboring gene uncharacterized LOC105378552 Neighboring gene uncharacterized LOC105378551 Neighboring gene neuropeptide S

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ45557

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
inhibitory postsynaptic potential IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
inhibitory postsynaptic potential ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
postsynaptic density IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
postsynaptic density ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
inhibitory synaptic factor 2A
Names
family with sequence similarity 196 member A
inhibitory synaptic protein 2
protein FAM196A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039762.3NP_001034851.1  inhibitory synaptic factor 2A

    See identical proteins and their annotated locations for NP_001034851.1

    Status: VALIDATED

    Source sequence(s)
    AK127465, AL390920, BC137112
    Consensus CDS
    CCDS31312.1
    UniProtKB/Swiss-Prot
    Q6ZSG2
    Related
    ENSP00000429763.1, ENST00000522781.6
    Conserved Domains (1) summary
    pfam15265
    Location:1479
    FAM196; FAM196 family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210226

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    127135430..127196591 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005252694.4XP_005252751.1  inhibitory synaptic factor 2A isoform X1

    See identical proteins and their annotated locations for XP_005252751.1

    UniProtKB/Swiss-Prot
    Q6ZSG2
    Conserved Domains (1) summary
    pfam15265
    Location:1479
    FAM196; FAM196 family
  2. XM_017016539.2XP_016872028.1  inhibitory synaptic factor 2A isoform X1

    UniProtKB/Swiss-Prot
    Q6ZSG2
    Conserved Domains (1) summary
    pfam15265
    Location:1479
    FAM196; FAM196 family
  3. XM_017016540.2XP_016872029.1  inhibitory synaptic factor 2A isoform X1

    UniProtKB/Swiss-Prot
    Q6ZSG2
    Conserved Domains (1) summary
    pfam15265
    Location:1479
    FAM196; FAM196 family
  4. XM_017016538.2XP_016872027.1  inhibitory synaptic factor 2A isoform X1

    UniProtKB/Swiss-Prot
    Q6ZSG2
    Conserved Domains (1) summary
    pfam15265
    Location:1479
    FAM196; FAM196 family
  5. XM_017016542.2XP_016872031.1  inhibitory synaptic factor 2A isoform X1

    UniProtKB/Swiss-Prot
    Q6ZSG2
    Conserved Domains (1) summary
    pfam15265
    Location:1479
    FAM196; FAM196 family
  6. XM_017016537.2XP_016872026.1  inhibitory synaptic factor 2A isoform X1

    UniProtKB/Swiss-Prot
    Q6ZSG2
    Conserved Domains (1) summary
    pfam15265
    Location:1479
    FAM196; FAM196 family
  7. XM_017016541.1XP_016872030.1  inhibitory synaptic factor 2A isoform X1

    UniProtKB/Swiss-Prot
    Q6ZSG2
    Conserved Domains (1) summary
    pfam15265
    Location:1479
    FAM196; FAM196 family
  8. XM_017016543.1XP_016872032.1  inhibitory synaptic factor 2A isoform X2

    Conserved Domains (1) summary
    pfam15265
    Location:1395
    FAM196; FAM196 family
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