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Foxb1 forkhead box B1 [ Mus musculus (house mouse) ]

Gene ID: 64290, updated on 12-Aug-2019

Summary

Official Symbol
Foxb1provided by MGI
Official Full Name
forkhead box B1provided by MGI
Primary source
MGI:MGI:1927549
See related
Ensembl:ENSMUSG00000059246
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
C43; Mf3; Twh; Fkh5; Foxb1a; Foxb1b; Hfh-e5.1
Expression
Biased expression in whole brain E14.5 (RPKM 3.7), CNS E14 (RPKM 2.6) and 4 other tissues See more
Orthologs

Genomic context

See Foxb1 in Genome Data Viewer
Location:
9 D; 9 38.76 cM
Exon count:
2
Annotation release Status Assembly Chr Location
108 current GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (69757710..69760940, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (69605517..69608747, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene predicted gene, 31469 Neighboring gene RIKEN cDNA B230323A14 gene Neighboring gene predicted gene, 31530 Neighboring gene zinc finger, BED domain containing 4 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC130499

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
anatomical structure morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
axon target recognition IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell migration in diencephalon IMP
Inferred from Mutant Phenotype
more info
PubMed 
epithelial cell differentiation involved in mammary gland alveolus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
floor plate development IMP
Inferred from Mutant Phenotype
more info
PubMed 
hypothalamus cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
inferior colliculus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
lactation IMP
Inferred from Mutant Phenotype
more info
PubMed 
mammary gland lobule development IMP
Inferred from Mutant Phenotype
more info
PubMed 
mammillary body development IEP
Inferred from Expression Pattern
more info
PubMed 
mammillary body development IMP
Inferred from Mutant Phenotype
more info
PubMed 
mammillothalamic axonal tract development IMP
Inferred from Mutant Phenotype
more info
PubMed 
midbrain development IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
somitogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
spinal cord development IEP
Inferred from Expression Pattern
more info
PubMed 
telencephalon cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
thalamus development IEP
Inferred from Expression Pattern
more info
PubMed 
urogenital system development IEP
Inferred from Expression Pattern
more info
PubMed 
visual learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
forkhead box protein B1
Names
forkhead box B1a
forkhead box B1b
mesoderm/mesenchyme forkhead 3
transcription factor FKH-5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022378.3NP_071773.2  forkhead box protein B1

    See identical proteins and their annotated locations for NP_071773.2

    Status: VALIDATED

    Source sequence(s)
    AC158992
    Consensus CDS
    CCDS40677.1
    UniProtKB/Swiss-Prot
    Q64732
    Related
    ENSMUSP00000096197.2, ENSMUST00000071281.4
    Conserved Domains (1) summary
    smart00339
    Location:13101
    FH; FORKHEAD

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p6 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p6 C57BL/6J

    Range
    69757710..69760940 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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