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ZNF487 zinc finger protein 487 [ Homo sapiens (human) ]

Gene ID: 642819, updated on 23-Nov-2021

Summary

Official Symbol
ZNF487provided by HGNC
Official Full Name
zinc finger protein 487provided by HGNC
Primary source
HGNC:HGNC:23488
See related
Ensembl:ENSG00000243660
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KRBO1; ZNF487P
Expression
Broad expression in testis (RPKM 13.6), gall bladder (RPKM 2.0) and 18 other tissues See more
Orthologs
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Genomic context

See ZNF487 in Genome Data Viewer
Location:
10q11.21
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (43436848..43483184)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (43932296..43978629)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein F Neighboring gene small nucleolar RNA, C/D box 3J Neighboring gene RNA, U7 small nuclear 193 pseudogene Neighboring gene uncharacterized LOC105379857 Neighboring gene zinc finger protein 12 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in chromatin ISA
Inferred from Sequence Alignment
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
putative zinc finger protein 487
Names
KRAB domain only 1
KRAB domain only protein 1
zinc finger protein 487, pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355444.3NP_001342373.2  putative zinc finger protein 487 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL450326
    Consensus CDS
    CCDS86084.1
    Related
    ENSP00000392335.2, ENST00000437590.3
    Conserved Domains (2) summary
    sd00019
    Location:158174
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:132
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  2. NM_001355445.3NP_001342374.2  putative zinc finger protein 487 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL450326
    Consensus CDS
    CCDS86084.1
    Related
    ENSP00000498527.1, ENST00000652684.1
    Conserved Domains (2) summary
    sd00019
    Location:158174
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:132
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  3. NM_001355446.3NP_001342375.2  putative zinc finger protein 487 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL450326
    Consensus CDS
    CCDS86084.1
    Conserved Domains (2) summary
    sd00019
    Location:158174
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:132
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  4. NM_001355447.2NP_001342376.1  putative zinc finger protein 487 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL450326
    Conserved Domains (2) summary
    sd00019
    Location:162178
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:748
    KRAB; KRAB box
  5. NM_001355448.2NP_001342377.1  putative zinc finger protein 487 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL450326
    Conserved Domains (2) summary
    smart00349
    Location:868
    KRAB; krueppel associated box
    sd00019
    Location:194210
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. NM_001355449.2NP_001342378.1  putative zinc finger protein 487 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL450326
    Conserved Domains (1) summary
    sd00019
    Location:127143
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. NM_001355450.1NP_001342379.1  putative zinc finger protein 487 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL450326
    Conserved Domains (1) summary
    sd00019
    Location:127143
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    43436848..43483184
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024448132.1XP_024303900.1  putative zinc finger protein 487 isoform X5

    Conserved Domains (2) summary
    sd00019
    Location:159175
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:233
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  2. XM_024448133.1XP_024303901.1  putative zinc finger protein 487 isoform X5

    Conserved Domains (2) summary
    sd00019
    Location:159175
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl02581
    Location:233
    KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
  3. XM_024448131.1XP_024303899.1  putative zinc finger protein 487 isoform X4

    Conserved Domains (2) summary
    sd00019
    Location:163179
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:849
    KRAB; KRAB box
  4. XM_024448129.1XP_024303897.1  putative zinc finger protein 487 isoform X2

    Conserved Domains (2) summary
    smart00349
    Location:969
    KRAB; krueppel associated box
    sd00019
    Location:195211
    ZF_C2H2; C2H2 Zn finger [structural motif]
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