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PAPOLA poly(A) polymerase alpha [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 641447, updated on 17-Aug-2024

Summary

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Official Symbol
PAPOLAprovided by VGNC
Official Full Name
poly(A) polymerase alphaprovided by VGNC
Primary source
VGNC:VGNC:84415
See related
Ensembl:ENSMMUG00000018610
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See PAPOLA in Genome Data Viewer
Location:
chromosome: 7
Exon count:
23
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (158696220..158761692)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (158783639..158849078)

Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene GSK3B interacting protein Neighboring gene phosphatidylethanolamine-binding protein 1 pseudogene Neighboring gene adenylate kinase 7 Neighboring gene uncharacterized LOC114679639 Neighboring gene ubiquitin-fold modifier-conjugating enzyme 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Form deprivation modulates retinal neurogenesis in primate experimental myopia. Tkatchenko AV, et al. Proc Natl Acad Sci U S A, 2006 Mar 21. PMID 16537371, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables poly(A) RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
poly(A) polymerase alpha
NP_001252826.1
XP_014999919.1
XP_014999920.1
XP_014999921.1
XP_014999922.1
XP_028705982.1
XP_028705983.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001265897.1 → NP_001252826.1  poly(A) polymerase alpha

    See identical proteins and their annotated locations for NP_001252826.1

    Status: PROVISIONAL

    Source sequence(s)
    JV046004
    UniProtKB/TrEMBL
    G7MW43, H9FP34
    Related
    ENSMMUP00000053333.1, ENSMMUT00000064078.2
    Conserved Domains (3) summary
    pfam04926
    Location:366 → 495
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:21 → 363
    PAP_central; Poly(A) polymerase central domain
    cl26091
    Location:501 → 646
    MotB_plug; Membrane MotB of proton-channel complex MotA/MotB

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041760.1 Reference Mmul_10 Primary Assembly

    Range
    158696220..158761692
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015144436.2 → XP_014999922.1  poly(A) polymerase alpha isoform X6

    UniProtKB/TrEMBL
    F6QV78, G7MW43
    Related
    ENSMMUP00000032588.3, ENSMMUT00000039510.3
    Conserved Domains (3) summary
    PTZ00418
    Location:9 → 567
    PTZ00418; Poly(A) polymerase; Provisional
    pfam04926
    Location:366 → 495
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:21 → 363
    PAP_central; Poly(A) polymerase central domain

  2. XM_015144433.2 → XP_014999919.1  poly(A) polymerase alpha isoform X1

    UniProtKB/TrEMBL
    G7MW43
    Conserved Domains (3) summary
    pfam04926
    Location:366 → 495
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:21 → 363
    PAP_central; Poly(A) polymerase central domain
    cl26091
    Location:501 → 645
    MotB_plug; Membrane MotB of proton-channel complex MotA/MotB

  3. XM_015144434.2 → XP_014999920.1  poly(A) polymerase alpha isoform X2

    UniProtKB/TrEMBL
    A0A1D5QFG2, G7MW43, H9FP32
    Related
    ENSMMUP00000046782.2, ENSMMUT00000076856.2
    Conserved Domains (3) summary
    PRK12799
    Location:501 → 646
    motB; flagellar motor protein MotB; Reviewed
    pfam04926
    Location:366 → 495
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:21 → 363
    PAP_central; Poly(A) polymerase central domain

  4. XM_015144435.2 → XP_014999921.1  poly(A) polymerase alpha isoform X4

    UniProtKB/TrEMBL
    F6QV47, G7MW43
    Related
    ENSMMUP00000032591.3, ENSMMUT00000039513.3
    Conserved Domains (3) summary
    PRK12799
    Location:501 → 646
    motB; flagellar motor protein MotB; Reviewed
    pfam04926
    Location:366 → 495
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:21 → 363
    PAP_central; Poly(A) polymerase central domain

  5. XM_028850149.1 → XP_028705982.1  poly(A) polymerase alpha isoform X3

    UniProtKB/TrEMBL
    G7MW43
    Conserved Domains (3) summary
    PRK12799
    Location:501 → 645
    motB; flagellar motor protein MotB; Reviewed
    pfam04926
    Location:366 → 495
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:21 → 363
    PAP_central; Poly(A) polymerase central domain

  6. XM_028850150.1 → XP_028705983.1  poly(A) polymerase alpha isoform X5

    UniProtKB/TrEMBL
    G7MW43
    Conserved Domains (3) summary
    PRK12799
    Location:501 → 645
    motB; flagellar motor protein MotB; Reviewed
    pfam04926
    Location:366 → 495
    PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
    pfam04928
    Location:21 → 363
    PAP_central; Poly(A) polymerase central domain
Nucleotide Protein
Heading Accession and Version

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