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CNP 2',3'-cyclic nucleotide 3' phosphodiesterase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 641337, updated on 20-May-2026
Official Symbol
CNPprovided by VGNC
Official Full Name
2',3'-cyclic nucleotide 3' phosphodiesteraseprovided by VGNC
Primary source
VGNC:VGNC:71279
See related
Ensembl:ENSMMUG00000016114
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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See CNP in Genome Data Viewer
Location:
chromosome: 16
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 16 NC_133421.1 (66307971..66319446)
103 previous assembly Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (53090947..53102448)

Chromosome 16 - NC_133421.1Genomic Context describing neighboring genes Neighboring gene ATP citrate lyase Neighboring gene outer dynein arm docking complex subunit 4 Neighboring gene uncharacterized LOC144335718 Neighboring gene uncharacterized LOC144335727 Neighboring gene uncharacterized LOC144335732 Neighboring gene DnaJ heat shock protein family (Hsp40) member C7 Neighboring gene uncharacterized LOC144335717

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cyclic nucleotide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Names
2', 3'-cyclic nucleotide phosphodiesterase
cyclic-CMP phosphodiesterase
NP_001030605.2
XP_028691293.1
XP_028691294.1
XP_077824635.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001035528.4 → NP_001030605.2  2',3'-cyclic-nucleotide 3'-phosphodiesterase

    Status: VALIDATED

    Source sequence(s)
    JBMGST020000016
    UniProtKB/TrEMBL
    F7GIP5, H9Z590, Q3LRT1
    Related
    ENSMMUP00000072014.1, ENSMMUT00000086462.1
    Conserved Domains (2) summary
    pfam05881
    Location:187 → 399
    CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
    cl26098
    Location:52 → 166
    AAA_33; AAA domain

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133421.1 Reference T2T-MMU8v2.0

    Range
    66307971..66319446
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028835460.2 → XP_028691293.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X1

    UniProtKB/TrEMBL
    A0A1D5R6V1, A0A5F8AC08
    Conserved Domains (3) summary
    pfam05881
    Location:167 → 379
    CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
    pfam13671
    Location:32 → 146
    AAA_33; AAA domain
    cl38914
    Location:369 → 400
    NP-I; nucleoside phosphorylase-I family

  2. XM_077968509.1 → XP_077824635.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X1

    UniProtKB/TrEMBL
    A0A1D5R6V1, A0A5F8AC08

  3. XM_028835461.2 → XP_028691294.1  2',3'-cyclic-nucleotide 3'-phosphodiesterase isoform X1

    UniProtKB/TrEMBL
    A0A1D5R6V1, A0A5F8AC08
    Related
    ENSMMUP00000074505.1
    Conserved Domains (3) summary
    pfam05881
    Location:167 → 379
    CNPase; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase)
    pfam13671
    Location:32 → 146
    AAA_33; AAA domain
    cl38914
    Location:369 → 400
    NP-I; nucleoside phosphorylase-I family
Nucleotide Protein
Heading Accession and Version

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