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NPVF neuropeptide VF precursor [ Homo sapiens (human) ]

Gene ID: 64111, updated on 5-Aug-2022

Summary

Official Symbol
NPVFprovided by HGNC
Official Full Name
neuropeptide VF precursorprovided by HGNC
Primary source
HGNC:HGNC:13782
See related
Ensembl:ENSG00000105954 MIM:616984; AllianceGenome:HGNC:13782
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RFRP; C7orf9
Summary
Predicted to enable signaling receptor binding activity. Involved in negative regulation of gonadotropin secretion. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See NPVF in Genome Data Viewer
Location:
7p15.3
Exon count:
3
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (25224570..25228486, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (25360013..25363930, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (25264189..25268105, complement)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901603 Neighboring gene uncharacterized LOC105375191 Neighboring gene ribosomal protein L7a pseudogene 41 Neighboring gene Sharpr-MPRA regulatory region 9537 Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Genome-wide association study of pre-eclampsia detects novel maternal single nucleotide polymorphisms and copy-number variants in subsets of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study cohort.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of gonadotropin secretion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in negative regulation of gonadotropin secretion IDA
Inferred from Direct Assay
more info
PubMed 
involved_in neuropeptide signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in neuropeptide signaling pathway NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
pro-FMRFamide-related neuropeptide VF
Names
FMRFamide-related peptide
FMRFamide-related peptides
RFamide-related peptide
neuropeptide NPVF

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022150.3NP_071433.3  pro-FMRFamide-related neuropeptide VF precursor

    See identical proteins and their annotated locations for NP_071433.3

    Status: VALIDATED

    Source sequence(s)
    AB040290, AF440392, BM714303
    Consensus CDS
    CCDS5395.1
    UniProtKB/Swiss-Prot
    Q96PI9, Q9HCQ7
    Related
    ENSP00000222674.2, ENST00000222674.2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    25224570..25228486 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    25360013..25363930 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)