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RTP4 receptor transporter protein 4 [ Homo sapiens (human) ]

Gene ID: 64108, updated on 22-Sep-2022

Summary

Official Symbol
RTP4provided by HGNC
Official Full Name
receptor transporter protein 4provided by HGNC
Primary source
HGNC:HGNC:23992
See related
Ensembl:ENSG00000136514 MIM:609350; AllianceGenome:HGNC:23992
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IFRG28; Z3CXXC4
Summary
Predicted to enable olfactory receptor binding activity. Involved in defense response to virus; detection of chemical stimulus involved in sensory perception of bitter taste; and protein targeting to membrane. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in urinary bladder (RPKM 8.4), duodenum (RPKM 6.0) and 25 other tissues See more
Orthologs
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Genomic context

See RTP4 in Genome Data Viewer
Location:
3q27.3
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (187368385..187372076)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (190185796..190189481)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (187086173..187089864)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene MBL associated serine protease 1 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr3:187003628-187004827 Neighboring gene uncharacterized LOC101929130 Neighboring gene small nucleolar RNA U13 Neighboring gene long intergenic non-protein coding RNA 2041

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables olfactory receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
receptor-transporting protein 4
Names
28 kDa interferon-responsive protein
28kD interferon responsive protein
3CxxC-type zinc finger protein 4
receptor (chemosensory) transporter protein 4
zinc finger, 3CxxC-type 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022147.3NP_071430.2  receptor-transporting protein 4

    See identical proteins and their annotated locations for NP_071430.2

    Status: VALIDATED

    Source sequence(s)
    AC068299, BC013161, CA413859
    Consensus CDS
    CCDS33910.1
    UniProtKB/Swiss-Prot
    Q96DX8, Q9H4F3
    Related
    ENSP00000259030.2, ENST00000259030.3
    Conserved Domains (1) summary
    pfam13695
    Location:48160
    zf-3CxxC; Zinc-binding domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    187368385..187372076
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791769.1 Reference GRCh38.p14 PATCHES

    Range
    178064..181755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    190185796..190189481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)