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PBLD phenazine biosynthesis like protein domain containing [ Homo sapiens (human) ]

Gene ID: 64081, updated on 12-Oct-2019

Summary

Official Symbol
PBLDprovided by HGNC
Official Full Name
phenazine biosynthesis like protein domain containingprovided by HGNC
Primary source
HGNC:HGNC:23301
See related
Ensembl:ENSG00000108187 MIM:612189
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MAWBP; MAWDBP; HEL-S-306
Expression
Biased expression in kidney (RPKM 94.0), duodenum (RPKM 62.5) and 5 other tissues See more
Orthologs

Genomic context

See PBLD in Genome Data Viewer
Location:
10q21.3
Exon count:
10
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (68282660..68332958, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (70042417..70096115, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2640 Neighboring gene keratin 19 pseudogene 4 Neighboring gene Sharpr-MPRA regulatory region 82 Neighboring gene heterogeneous nuclear ribonucleoprotein H3 Neighboring gene RUN and FYVE domain containing 2 Neighboring gene ribosomal protein L26 pseudogene 29 Neighboring gene DNA replication helicase/nuclease 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide association study of optic disc parameters.
NHGRI GWA Catalog
Genome-wide association identifies ATOH7 as a major gene determining human optic disc size.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ14767, FLJ35507

Gene Ontology Provided by GOA

Function Evidence Code Pubs
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
isomerase activity IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome HDA PubMed 

General protein information

Preferred Names
phenazine biosynthesis-like domain-containing protein
Names
MAWD-binding protein
epididymis secretory protein Li 306
epididymis secretory sperm binding protein
NP_001028255.1
NP_071412.2
XP_005270085.1
XP_011538362.1
XP_016872002.1
XP_016872003.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033083.2NP_001028255.1  phenazine biosynthesis-like domain-containing protein isoform b

    See identical proteins and their annotated locations for NP_001028255.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) includes a different 3' terminal exon compared to variant 1. The resulting protein (isoform b) has a shorter, distinct C-terminus compared to isoform a.
    Source sequence(s)
    AC016395, AI114748, AI439144, CB121561
    Consensus CDS
    CCDS44413.1
    UniProtKB/Swiss-Prot
    P30039
    Related
    ENSP00000476306.1, ENST00000495025.2
    Conserved Domains (1) summary
    cl19724
    Location:1244
    DAP_epimerase; Diaminopimelate epimerase
  2. NM_022129.4NP_071412.2  phenazine biosynthesis-like domain-containing protein isoform a

    See identical proteins and their annotated locations for NP_071412.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
    Source sequence(s)
    AC016395, AI114748, CB121561
    Consensus CDS
    CCDS7277.2
    UniProtKB/Swiss-Prot
    P30039
    UniProtKB/TrEMBL
    A0A024QZK5
    Related
    ENSP00000351619.2, ENST00000358769.7
    Conserved Domains (1) summary
    cl27516
    Location:9284
    PhzC-PhzF; Phenazine biosynthesis-like protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    68282660..68332958 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011540060.3XP_011538362.1  phenazine biosynthesis-like domain-containing protein isoform X2

    Conserved Domains (1) summary
    cl19724
    Location:1234
    DAP_epimerase; Diaminopimelate epimerase
  2. XM_005270028.4XP_005270085.1  phenazine biosynthesis-like domain-containing protein isoform X1

    See identical proteins and their annotated locations for XP_005270085.1

    UniProtKB/Swiss-Prot
    P30039
    UniProtKB/TrEMBL
    A0A024QZK5
    Related
    ENSP00000308466.4, ENST00000309049.8
    Conserved Domains (1) summary
    cl27516
    Location:9284
    PhzC-PhzF; Phenazine biosynthesis-like protein
  3. XM_017016513.1XP_016872002.1  phenazine biosynthesis-like domain-containing protein isoform X2

    Conserved Domains (1) summary
    cl19724
    Location:1234
    DAP_epimerase; Diaminopimelate epimerase
  4. XM_017016514.1XP_016872003.1  phenazine biosynthesis-like domain-containing protein isoform X3

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