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Pygl glycogen phosphorylase L [ Rattus norvegicus (Norway rat) ]

Gene ID: 64035, updated on 19-Apr-2019

Summary

Official Symbol
Pyglprovided by RGD
Official Full Name
glycogen phosphorylase Lprovided by RGD
Primary source
RGD:620687
See related
Ensembl:ENSRNOG00000006388
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
catalyzes the rate-limiting step of glycogen catabolism [RGD, Feb 2006]
Expression
Biased expression in Liver (RPKM 825.9), Thymus (RPKM 319.3) and 4 other tissues See more
Orthologs

Genomic context

See Pygl in Genome Data Viewer
Location:
6q24
Exon count:
20
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (92597759..92643734, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 6 NC_005105.3 (102045144..102091119, complement)

Chromosome 6 - NC_005105.4Genomic Context describing neighboring genes Neighboring gene ninein Neighboring gene abhydrolase domain containing 12B Neighboring gene tripartite motif-containing 9 Neighboring gene uncharacterized LOC102549102

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
AMP binding IEA
Inferred from Electronic Annotation
more info
 
AMP binding ISO
Inferred from Sequence Orthology
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATP binding ISO
Inferred from Sequence Orthology
more info
PubMed 
SHG alpha-glucan phosphorylase activity IEA
Inferred from Electronic Annotation
more info
 
bile acid binding IEA
Inferred from Electronic Annotation
more info
 
bile acid binding ISO
Inferred from Sequence Orthology
more info
PubMed 
carbohydrate binding IDA
Inferred from Direct Assay
more info
PubMed 
drug binding IDA
Inferred from Direct Assay
more info
PubMed 
drug binding ISO
Inferred from Sequence Orthology
more info
PubMed 
glycogen phosphorylase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glycogen phosphorylase activity IDA
Inferred from Direct Assay
more info
PubMed 
glycogen phosphorylase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
glycogen phosphorylase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
linear malto-oligosaccharide phosphorylase activity IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity IC
Inferred by Curator
more info
PubMed 
protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
purine nucleobase binding IEA
Inferred from Electronic Annotation
more info
 
purine nucleobase binding ISO
Inferred from Sequence Orthology
more info
PubMed 
pyridoxal phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vitamin binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
5-phosphoribose 1-diphosphate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 
glucose homeostasis ISO
Inferred from Sequence Orthology
more info
PubMed 
glycogen catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glycogen catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
glycogen metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
glycogen metabolic process ISO
Inferred from Sequence Orthology
more info
PubMed 
necroptotic process IEA
Inferred from Electronic Annotation
more info
 
necroptotic process ISO
Inferred from Sequence Orthology
more info
PubMed 
response to bacterium IEA
Inferred from Electronic Annotation
more info
 
response to bacterium ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
glycogen phosphorylase, liver form
Names
liver glycogen phosphorylase
phosphorylase, glycogen, liver
NP_071604.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022268.1NP_071604.1  glycogen phosphorylase, liver form

    See identical proteins and their annotated locations for NP_071604.1

    Status: PROVISIONAL

    Source sequence(s)
    X63515
    UniProtKB/Swiss-Prot
    P09811
    Related
    ENSRNOP00000009183.3, ENSRNOT00000009183.5
    Conserved Domains (2) summary
    cd04300
    Location:29827
    GT1_Glycogen_Phosphorylase; This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of ...
    TIGR02093
    Location:32827
    P_ylase; glycogen/starch/alpha-glucan phosphorylases

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005105.4 Reference Rnor_6.0 Primary Assembly

    Range
    92597759..92643734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000074.1 Alternate Rn_Celera

    Range
    87191869..87228313 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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