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PCGEM1 PCGEM1 prostate-specific transcript [ Homo sapiens (human) ]

Gene ID: 64002, updated on 30-Oct-2022

Summary

Official Symbol
PCGEM1provided by HGNC
Official Full Name
PCGEM1 prostate-specific transcriptprovided by HGNC
Primary source
HGNC:HGNC:30145
See related
Ensembl:ENSG00000227418 MIM:605443; AllianceGenome:HGNC:30145
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PCAT9; LINC00071; NCRNA00071
Summary
This gene produces a long non-coding RNA that is overexpressed in prostate cancer and may act a marker for tumor progression. This RNA may act a negative regulator of apoptosis, and may promote activity of androgen receptor and Myc. [provided by RefSeq, Dec 2017]
Expression
Restricted expression toward prostate (RPKM 5.3) See more
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Genomic context

See PCGEM1 in Genome Data Viewer
Location:
2q32.3
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (192749845..192776899)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (193238254..193265316)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (193614571..193641625)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 5853 Neighboring gene transmembrane protein with EGF like and two follistatin like domains 2 Neighboring gene CAVIN2 and TMEFF2 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 3165 Neighboring gene ribosomal protein S17 pseudogene 8 Neighboring gene uncharacterized LOC107985969 Neighboring gene SLC44A3 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

EBI GWAS Catalog

Description
Biological insights from 108 schizophrenia-associated genetic loci.
EBI GWAS Catalog
Genome-wide association study identifies five new schizophrenia loci.
EBI GWAS Catalog
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
EBI GWAS Catalog

General gene information

Other Names

  • PCGEM1, prostate-specific transcript (non-protein coding)
  • long intergenic non-protein coding RNA 71
  • prostate cancer associated transcript 9
  • prostate cancer gene expression marker 1
  • prostate-specific transcript 1 (non-protein coding)

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_002769.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AF223389
    Related
    ENST00000454040.5
  2. NR_152587.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC013401

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    192749845..192776899
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    193238254..193265316
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)