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DMRTA2 DMRT like family A2 [ Homo sapiens (human) ]

Gene ID: 63950, updated on 4-Jun-2020

Summary

Official Symbol
DMRTA2provided by HGNC
Official Full Name
DMRT like family A2provided by HGNC
Primary source
HGNC:HGNC:13908
See related
Ensembl:ENSG00000142700 MIM:614804
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See DMRTA2 in Genome Data Viewer
Location:
1p32.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (50417550..50423443, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (50883223..50889119, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105378714 Neighboring gene high mobility group box 1 pseudogene 45 Neighboring gene FCF1 pseudogene 6 Neighboring gene FAF1 antisense RNA 1 Neighboring gene Fas associated factor 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific ISM
Inferred from Sequence Model
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cerebral cortex regionalization IEA
Inferred from Electronic Annotation
more info
 
dopaminergic neuron differentiation IEA
Inferred from Electronic Annotation
more info
 
neuron fate specification IEA
Inferred from Electronic Annotation
more info
 
positive regulation of neuroblast proliferation IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
skeletal muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 

General protein information

Preferred Names
doublesex- and mab-3-related transcription factor A2
Names
doublesex- and mab-3-related transcription factor 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032110.3NP_115486.1  doublesex- and mab-3-related transcription factor A2

    See identical proteins and their annotated locations for NP_115486.1

    Status: VALIDATED

    Source sequence(s)
    AJ301580, AL049637, BM675521, BQ941189, CF242912
    Consensus CDS
    CCDS44141.1
    UniProtKB/Swiss-Prot
    Q96SC8
    Related
    ENSP00000383909.3, ENST00000404795.4
    Conserved Domains (2) summary
    cd14418
    Location:312353
    CUE_DMA_DMRTA2; CUE-like DMA domain found in doublesex- and mab-3-related transcription factor A2 (DMRTA2)
    pfam00751
    Location:66112
    DM; DM DNA binding domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    50417550..50423443 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541937.2XP_011540239.1  doublesex- and mab-3-related transcription factor A2 isoform X1

    See identical proteins and their annotated locations for XP_011540239.1

    UniProtKB/Swiss-Prot
    Q96SC8
    Related
    ENSP00000399370.1, ENST00000418121.5
    Conserved Domains (2) summary
    cd14418
    Location:312353
    CUE_DMA_DMRTA2; CUE-like DMA domain found in doublesex- and mab-3-related transcription factor A2 (DMRTA2)
    pfam00751
    Location:66112
    DM; DM DNA binding domain
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