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CXorf56 chromosome X open reading frame 56 [ Homo sapiens (human) ]

Gene ID: 63932, updated on 25-Apr-2020

Summary

Official Symbol
CXorf56provided by HGNC
Official Full Name
chromosome X open reading frame 56provided by HGNC
Primary source
HGNC:HGNC:26239
See related
Ensembl:ENSG00000018610 MIM:301012
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MRX107
Summary
While this gene is well-supported by transcript data, no functional information on its protein products is currently available. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Expression
Ubiquitous expression in thyroid (RPKM 6.7), fat (RPKM 5.9) and 25 other tissues See more
Orthologs

Genomic context

See CXorf56 in Genome Data Viewer
Location:
Xq24
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (119538149..119565409, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (118672112..118699397, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene SLC25A5 antisense RNA 1 Neighboring gene solute carrier family 25 member 5 Neighboring gene uncharacterized LOC107985719 Neighboring gene Sharpr-MPRA regulatory region 9216 Neighboring gene ubiquitin conjugating enzyme E2 A Neighboring gene NFKB repressing factor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ22965

Gene Ontology Provided by GOA

Component Evidence Code Pubs
cell body ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_016378.1 RefSeqGene

    Range
    5026..32286
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001170569.1NP_001164040.1  UPF0428 protein CXorf56 isoform 2

    See identical proteins and their annotated locations for NP_001164040.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice junction at the 3' end of the first exon, which causes a frameshift and use of a downstream AUG. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AC004000, BQ223940, DA590933, DA921725
    Consensus CDS
    CCDS55484.1
    UniProtKB/Swiss-Prot
    Q9H5V9
    Related
    ENSP00000320345.4, ENST00000320339.8
  2. NM_001170570.2NP_001164041.1  UPF0428 protein CXorf56 isoform 3

    See identical proteins and their annotated locations for NP_001164041.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    AC004000, AK298877, BQ223940, DB033119
    Consensus CDS
    CCDS55485.1
    UniProtKB/Swiss-Prot
    Q9H5V9
    Related
    ENSP00000441786.1, ENST00000536133.2
  3. NM_022101.4NP_071384.1  UPF0428 protein CXorf56 isoform 1

    See identical proteins and their annotated locations for NP_071384.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC004000, BQ223940, DA921725
    UniProtKB/Swiss-Prot
    Q9H5V9
    Related
    ENSP00000494123.1, ENST00000644802.1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    119538149..119565409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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