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SAA4 serum amyloid A4, constitutive [ Homo sapiens (human) ]

Gene ID: 6291, updated on 7-Jun-2020

Summary

Official Symbol
SAA4provided by HGNC
Official Full Name
serum amyloid A4, constitutiveprovided by HGNC
Primary source
HGNC:HGNC:10516
See related
Ensembl:ENSG00000148965 MIM:104752
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CSAA; C-SAA
Expression
Restricted expression toward liver (RPKM 339.3) See more
Orthologs

Genomic context

See SAA4 in Genome Data Viewer
Location:
11p15.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (18231355..18236802, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (18252902..18258384, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene MAS related GPR family member X13, pseudogene Neighboring gene SLC25A51 pseudogene 4 Neighboring gene SAA2-SAA4 readthrough Neighboring gene serum amyloid A2 Neighboring gene RNA, 5S ribosomal pseudogene 333 Neighboring gene ST13, Hsp70 interacting protein pseudogene 5

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Readthrough SAA2-SAA4

Readthrough gene: SAA2-SAA4, Included gene: SAA2

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
acute-phase response IEA
Inferred from Electronic Annotation
more info
 
positive chemotaxis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
extracellular exosome HDA PubMed 
extracellular region NAS
Non-traceable Author Statement
more info
PubMed 
high-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
serum amyloid A-4 protein
Names
constitutively expressed serum amyloid A protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006512.4NP_006503.2  serum amyloid A-4 protein precursor

    See identical proteins and their annotated locations for NP_006503.2

    Status: VALIDATED

    Source sequence(s)
    AV699045, BC007026, BG569210
    Consensus CDS
    CCDS7832.1
    UniProtKB/Swiss-Prot
    P35542
    Related
    ENSP00000278222.4, ENST00000278222.7
    Conserved Domains (1) summary
    smart00197
    Location:21130
    SAA; Serum amyloid A proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    18231355..18236802 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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