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BDNF brain derived neurotrophic factor [ Homo sapiens (human) ]

Gene ID: 627, updated on 20-Sep-2020

Summary

Official Symbol
BDNFprovided by HGNC
Official Full Name
brain derived neurotrophic factorprovided by HGNC
Primary source
HGNC:HGNC:1033
See related
Ensembl:ENSG00000176697 MIM:113505
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ANON2; BULN2
Summary
This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]
Expression
Biased expression in brain (RPKM 3.0), lung (RPKM 1.2) and 11 other tissues See more
Orthologs

Genomic context

See BDNF in Genome Data Viewer
Location:
11p14.1
Exon count:
12
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (27654893..27722030, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (27676440..27743605, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene BDNF antisense RNA Neighboring gene long intergenic non-protein coding RNA 678 Neighboring gene Sharpr-MPRA regulatory region 8127 Neighboring gene chromobox 3 pseudogene 1 Neighboring gene heat shock protein 90 alpha family class A member 2, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
GeneReviews: Not available
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.
GeneReviews: Not available
Genome wide association study identifies KCNMA1 contributing to human obesity.
GeneReviews: Not available
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.
GeneReviews: Not available
Genome-wide meta-analyses identify multiple loci associated with smoking behavior.
GeneReviews: Not available
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
GeneReviews: Not available
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.
GeneReviews: Not available
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
GeneReviews: Not available
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
GeneReviews: Not available

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env Co-exposure of human fetal neurons to brain-derived neurotrophic factor (BDNF) and HIV-1 gp120 leads to a dose-dependent increase in BDNF-induced somatostatin (SRIF) production PubMed
Tat tat The gene expression of brain-derived neurotrophic factor is significantly upregulated in both clade B and clade C Tat treated SK-N-MC cells PubMed
tat Human BDNF is protective to neuroblastoma cells exposed to HIV-1 Tat PubMed
tat HIV-1 Tat increases proapoptotic proBDNF and decreases the mature BDNF protein in hippocampal neurons PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC34632

Gene Ontology Provided by GOA

Function Evidence Code Pubs
growth factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nerve growth factor receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
activation of phospholipase C activity TAS
Traceable Author Statement
more info
 
axon extension IEA
Inferred from Electronic Annotation
more info
 
axon guidance TAS
Traceable Author Statement
more info
PubMed 
axon target recognition IEA
Inferred from Electronic Annotation
more info
 
behavioral fear response IEA
Inferred from Electronic Annotation
more info
 
brain-derived neurotrophic factor receptor signaling pathway TAS
Traceable Author Statement
more info
PubMed 
circadian rhythm IEA
Inferred from Electronic Annotation
more info
 
collateral sprouting IDA
Inferred from Direct Assay
more info
PubMed 
dendrite development IEA
Inferred from Electronic Annotation
more info
 
dendrite extension IEA
Inferred from Electronic Annotation
more info
 
feeding behavior IEA
Inferred from Electronic Annotation
more info
 
gamma-aminobutyric acid signaling pathway IEA
Inferred from Electronic Annotation
more info
 
glutamate secretion IEA
Inferred from Electronic Annotation
more info
 
inhibitory postsynaptic potential IEA
Inferred from Electronic Annotation
more info
 
inner ear development IEA
Inferred from Electronic Annotation
more info
 
mechanoreceptor differentiation IEA
Inferred from Electronic Annotation
more info
 
memory IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
modulation of chemical synaptic transmission IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of apoptotic signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of myotube differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of neuroblast proliferation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of neuron apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of synaptic transmission, GABAergic IEA
Inferred from Electronic Annotation
more info
 
nerve development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nerve growth factor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nervous system development TAS
Traceable Author Statement
more info
PubMed 
neuron projection morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuron recognition IEA
Inferred from Electronic Annotation
more info
 
neurotrophin TRK receptor signaling pathway TAS
Traceable Author Statement
more info
 
peripheral nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of brain-derived neurotrophic factor receptor signaling pathway TAS
Traceable Author Statement
more info
PubMed 
positive regulation of collateral sprouting IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of collateral sprouting IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of neuron projection development ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of non-membrane spanning protein tyrosine kinase activity TAS
Traceable Author Statement
more info
 
positive regulation of peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of synapse assembly IDA
Inferred from Direct Assay
more info
PubMed 
regulation of neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of protein localization to cell surface TAS
Traceable Author Statement
more info
PubMed 
regulation of retinal cell programmed cell death IEA
Inferred from Electronic Annotation
more info
 
regulation of synaptic plasticity IEA
Inferred from Electronic Annotation
more info
 
response to drug IEA
Inferred from Electronic Annotation
more info
 
retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
synapse assembly IDA
Inferred from Direct Assay
more info
PubMed 
taste bud development IEA
Inferred from Electronic Annotation
more info
 
transmembrane receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ureteric bud development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular region TAS
Traceable Author Statement
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
 
nuclear speck IDA
Inferred from Direct Assay
more info
 
perinuclear region of cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
postsynapse IEA
Inferred from Electronic Annotation
more info
 
secretory granule IEA
Inferred from Electronic Annotation
more info
 
synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
brain-derived neurotrophic factor
Names
abrineurin
neurotrophin

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_011794.1 RefSeqGene

    Range
    5001..72164
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001143805.1NP_001137277.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_001137277.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7), also known as IIa or BDNF2A, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    EF674517
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000432035.1, ENST00000525950.5
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  2. NM_001143806.1NP_001137278.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_001137278.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8), also known as IIb or BDNF2B, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    EF674518
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000379302.3, ENST00000395978.7
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  3. NM_001143807.2NP_001137279.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_001137279.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), also known as III or BDNF3, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    AC104563, KF459669
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000435805.1, ENST00000532997.5
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  4. NM_001143808.2NP_001137280.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_001137280.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), also known as Va, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    AC104563, KF459669
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000379307.3, ENST00000395983.7
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  5. NM_001143809.2NP_001137281.1  brain-derived neurotrophic factor isoform d

    See identical proteins and their annotated locations for NP_001137281.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), also known as Vb, represents use of an alternate promoter and differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (d) contains a longer N-terminus and lacks a predicted signal peptide compared to isoform a.
    Source sequence(s)
    AC104563, KF459669
    UniProtKB/Swiss-Prot
    P23560
    Conserved Domains (1) summary
    smart00140
    Location:162269
    NGF; Nerve growth factor (NGF or beta-NGF)
  6. NM_001143810.2NP_001137282.1  brain-derived neurotrophic factor isoform e

    See identical proteins and their annotated locations for NP_001137282.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18), also known as V-VIII, represents use of an alternate promoter and differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (e) contains a longer N-terminus and lacks a predicted signal peptide compared to isoform a.
    Source sequence(s)
    AC104563, KF455346, KF459669
    Consensus CDS
    CCDS44558.1
    UniProtKB/Swiss-Prot
    P23560
    Related
    ENSP00000414303.1, ENST00000438929.5
    Conserved Domains (1) summary
    smart00140
    Location:215322
    NGF; Nerve growth factor (NGF or beta-NGF)
  7. NM_001143811.2NP_001137283.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_001137283.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), also known as V-VIII-VIIIh, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    AC104563, KF455346, KF459669
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  8. NM_001143812.2NP_001137284.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_001137284.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), also known as Vh, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    AC104563, KF459669
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000435564.1, ENST00000530861.5
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  9. NM_001143813.2NP_001137285.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_001137285.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), also known as VIa, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    AC104563, KF459669
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000432376.1, ENST00000533246.5
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  10. NM_001143814.2NP_001137286.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_001137286.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), also known as VIb-IXbd, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    AC104563, KF459669
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000400502.1, ENST00000418212.5
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  11. NM_001143816.2NP_001137288.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_001137288.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), also known as IXabd, differs in the 5' UTR compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    AC104563, KF459669
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000389345.2, ENST00000439476.6
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  12. NM_001709.5NP_001700.2  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_001700.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4), also known as VIb or BDNF5, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    AC104563, KF459669
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000349084.4, ENST00000356660.9
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  13. NM_170731.5NP_733927.1  brain-derived neurotrophic factor isoform b precursor

    See identical proteins and their annotated locations for NP_733927.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3), also known as I, BDNF1, or 1-5, represents use of an alternate promoter and differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (b) contains a longer N-terminus compared to isoform a. This isoform (b) may undergo proteolytic processing similar to isoform a.
    Source sequence(s)
    AC103796, AC104563, KF459669
    Consensus CDS
    CCDS7865.1
    UniProtKB/Swiss-Prot
    P23560
    Related
    ENSP00000320002.6, ENST00000314915.6
    Conserved Domains (1) summary
    smart00140
    Location:141248
    NGF; Nerve growth factor (NGF or beta-NGF)
  14. NM_170732.4NP_733928.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_733928.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2), also known as IIc, BDNF2C, or 2-5, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    EF674519
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000379305.3, ENST00000395981.7
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  15. NM_170733.4NP_733929.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_733929.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), also known as IV, BDNF4, or 3-5, differs in the 5' UTR and represents use of an alternate promoter compared to variant 1. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    AC104563, KF459669
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENST00000584049.5
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)
  16. NM_170734.4NP_733930.1  brain-derived neurotrophic factor isoform c

    See identical proteins and their annotated locations for NP_733930.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6), also known as VIIb, BDNF6B, or 4I-5, represents use of an alternate promoter and differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (c) contains a longer N-terminus and lacks a predicted signal peptide compared to isoform a.
    Source sequence(s)
    AC104563, KF459669
    Consensus CDS
    CCDS41628.1
    UniProtKB/Swiss-Prot
    P23560
    Related
    ENSP00000379309.2, ENST00000395986.6
    Conserved Domains (1) summary
    smart00140
    Location:148255
    NGF; Nerve growth factor (NGF or beta-NGF)
  17. NM_170735.6NP_733931.1  brain-derived neurotrophic factor isoform a preproprotein

    See identical proteins and their annotated locations for NP_733931.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1), also known as IX, represents the longest transcript. Variants 1, 2, 4, 5, and 7-16 encode the same isoform (a).
    Source sequence(s)
    AC104563, KF459669
    Consensus CDS
    CCDS7866.1
    UniProtKB/Swiss-Prot
    P23560
    UniProtKB/TrEMBL
    A0A0E3SU01
    Related
    ENSP00000437138.1, ENST00000525528.1
    Conserved Domains (1) summary
    smart00140
    Location:133240
    NGF; Nerve growth factor (NGF or beta-NGF)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    27654893..27722030 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011520280.2XP_011518582.1  brain-derived neurotrophic factor isoform X1

    See identical proteins and their annotated locations for XP_011518582.1

    UniProtKB/Swiss-Prot
    P23560
    Conserved Domains (1) summary
    smart00140
    Location:215322
    NGF; Nerve growth factor (NGF or beta-NGF)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001143815.1: Suppressed sequence

    Description
    NM_001143815.1: This RefSeq was temporarily suppressed because currently there is not sufficient data to support this transcript, which contains non-consensus splice sites in the 5' UTR.
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