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Cks1brt CDC28 protein kinase 1b, retrogene [ Mus musculus (house mouse) ]

Gene ID: 624855, updated on 8-Feb-2024

Summary

Official Symbol
Cks1brtprovided by MGI
Official Full Name
CDC28 protein kinase 1b, retrogeneprovided by MGI
Primary source
MGI:MGI:3643620
See related
Ensembl:ENSMUSG00000062687 AllianceGenome:MGI:3643620
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm6531; EG624855
Summary
Predicted to enable several functions, including cyclin-dependent protein serine/threonine kinase activator activity; histone binding activity; and ubiquitin binding activity. Predicted to be involved in regulation of mitotic cell cycle. Predicted to be part of SCF ubiquitin ligase complex and cyclin-dependent protein kinase holoenzyme complex. Orthologous to human CKS1B (CDC28 protein kinase regulatory subunit 1B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

See Cks1brt in Genome Data Viewer
Location:
8 C3; 8 41.55 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (85878553..85900251)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (85151924..85173622)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 791 Neighboring gene predicted gene, 42031 Neighboring gene STARR-seq mESC enhancer starr_22151 Neighboring gene predicted gene, 33296 Neighboring gene zinc finger protein 46 pseudogene Neighboring gene olfactory receptor family 7 subfamily C member 19 Neighboring gene STARR-seq mESC enhancer starr_22152 Neighboring gene VPS35 retromer complex component

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cyclin-dependent protein serine/threonine kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in regulation of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cyclin-dependent protein kinase holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein LOC624855

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037922.3NP_001033011.1  uncharacterized protein LOC624855

    See identical proteins and their annotated locations for NP_001033011.1

    Status: VALIDATED

    Source sequence(s)
    AC159275, AC163703
    Consensus CDS
    CCDS52622.1
    UniProtKB/TrEMBL
    Q3UNC9, Q9D0L3
    Related
    ENSMUSP00000147685.2, ENSMUST00000211617.2
    Conserved Domains (1) summary
    pfam01111
    Location:2590
    CKS; Cyclin-dependent kinase regulatory subunit

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    85878553..85900251
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)