Gm14137 predicted gene 14137 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Gm14137provided by MGI
Official Full Name: predicted gene 14137provided by MGI
Primary source: MGI:MGI:3651144
See related: Ensembl:ENSMUSG00000055926 AllianceGenome:MGI:3651144
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to be involved in Rho protein signal transduction; positive regulation of cellular component biogenesis; and regulation of cell shape. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm; cytoskeleton; and plasma membrane. Orthologous to human C15orf62 (chromosome 15 open reading frame 62). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human all
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Genomic context

Location:: 2; 2 E5

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (119004990..119008049)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (119174509..119177568)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

Homologs of the Gm14137 gene: The Gm14137 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, and chicken.
Orthologs from Annotation Pipeline: 330 organisms have orthologs with human gene Gm14137
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables small GTPase binding	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of actin filament polymerization	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in positive regulation of pseudopodium assembly	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in regulation of cell shape	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info	PubMed
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein C15orf62 homolog, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001039223.4 → NP_001034312.2 uncharacterized protein C15orf62 homolog, mitochondrial

Status: VALIDATED

Source sequence(s)

AL772264

Consensus CDS

CCDS16594.2

UniProtKB/Swiss-Prot

Q8CE97

Related

ENSMUSP00000159192.2, ENSMUST00000239130.2

Conserved Domains (1) summary

pfam14957
Location:110 → 165

BORG_CEP; Cdc42 effector