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Faiml Fas apoptotic inhibitory molecule like [ Mus musculus (house mouse) ]

Gene ID: 623459, updated on 8-Feb-2024

Summary

Official Symbol
Faimlprovided by MGI
Official Full Name
Fas apoptotic inhibitory molecule likeprovided by MGI
Primary source
MGI:MGI:3647754
See related
Ensembl:ENSMUSG00000096316 AllianceGenome:MGI:3647754
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm6432; EG623459
Summary
Predicted to be involved in I-kappaB kinase/NF-kappaB signaling; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; and positive regulation of neurogenesis. Orthologous to human FAIM (Fas apoptotic inhibitory molecule). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward testis adult (RPKM 5.8) See more
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Genomic context

Location:
9 E3.3; 9 51.44 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (99111429..99119292, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (99229376..99237239, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33857 Neighboring gene centrosomal protein 70 Neighboring gene predicted gene 2950 Neighboring gene STARR-positive B cell enhancer ABC_E9773 Neighboring gene STARR-seq mESC enhancer starr_25018 Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 8 pseudogene Neighboring gene RIKEN cDNA 4930422M22 gene Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 14 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
fas apoptotic inhibitory molecule 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001244762.1NP_001231691.1  fas apoptotic inhibitory molecule 1-like

    See identical proteins and their annotated locations for NP_001231691.1

    Status: VALIDATED

    Source sequence(s)
    AC159899
    Consensus CDS
    CCDS57691.1
    UniProtKB/TrEMBL
    J3QPY3
    Related
    ENSMUSP00000137541.2, ENSMUST00000178051.8
    Conserved Domains (1) summary
    pfam06905
    Location:3173
    FAIM1; Fas apoptotic inhibitory molecule (FAIM1)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    99111429..99119292 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)