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Majin membrane anchored junction protein [ Mus musculus (house mouse) ]

Gene ID: 622554, updated on 8-Feb-2024

Summary

Official Symbol
Majinprovided by MGI
Official Full Name
membrane anchored junction proteinprovided by MGI
Primary source
MGI:MGI:1923913
See related
Ensembl:ENSMUSG00000024786 AllianceGenome:MGI:1923913
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700123I01Rik
Summary
Predicted to enable DNA binding activity. Involved in homologous chromosome pairing at meiosis and meiotic attachment of telomere to nuclear envelope. Located in chromosome, telomeric region. Is integral component of nuclear inner membrane. Orthologous to human MAJIN (membrane anchored junction protein). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 2.9) and large intestine adult (RPKM 0.2) See more
Orthologs
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Genomic context

See Majin in Genome Data Viewer
Location:
19 A; 19 4.34 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (6234358..6274349)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (6184345..6224230)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted pseudogene 5510 Neighboring gene basic leucine zipper transcription factor, ATF-like 2 Neighboring gene protein phosphatase 2, regulatory subunit B', beta Neighboring gene STARR-positive B cell enhancer ABC_E9990 Neighboring gene STARR-positive B cell enhancer ABC_E5681 Neighboring gene glycoprotein hormone alpha 2 Neighboring gene STARR-positive B cell enhancer ABC_E619 Neighboring gene autophagy related 2A

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
  • Endonuclease-mediated (3)  1 citation

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in chromosome, telomeric region IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear envelope IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
membrane-anchored junction protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001165919.2NP_001159391.1  membrane-anchored junction protein isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC127556
    Consensus CDS
    CCDS50364.1
    UniProtKB/Swiss-Prot
    E9Q4N4, Q9D992
    UniProtKB/TrEMBL
    B2RQN5
    Related
    ENSMUSP00000109156.2, ENSMUST00000113528.2
    Conserved Domains (1) summary
    pfam15077
    Location:1240
    MAJIN; Membrane-anchored junction protein
  2. NM_001377074.1NP_001364003.1  membrane-anchored junction protein isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC127556
    Conserved Domains (1) summary
    pfam15077
    Location:1182
    MAJIN; Membrane-anchored junction protein
  3. NM_001377075.1NP_001364004.1  membrane-anchored junction protein isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC127556
    Related
    ENSMUSP00000025699.3, ENSMUST00000025699.9
    Conserved Domains (1) summary
    pfam15077
    Location:1108
    MAJIN; Membrane-anchored junction protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    6234358..6274349
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036161650.1XP_036017543.1  membrane-anchored junction protein isoform X2

    Conserved Domains (1) summary
    pfam15077
    Location:1129
    MAJIN; Membrane-anchored junction protein
  2. XM_011248644.3XP_011246946.1  membrane-anchored junction protein isoform X1

    UniProtKB/TrEMBL
    B2RQN5
    Conserved Domains (1) summary
    pfam15077
    Location:14221
    MAJIN; Membrane-anchored junction protein