U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tmem253 transmembrane protein 253 [ Mus musculus (house mouse) ]

Gene ID: 619301, updated on 8-Nov-2022

Summary

Official Symbol
Tmem253provided by MGI
Official Full Name
transmembrane protein 253provided by MGI
Primary source
MGI:MGI:3588246
See related
Ensembl:ENSMUSG00000072571 AllianceGenome:MGI:3588246
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
G630016D24Rik
Summary
Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TMEM253 (transmembrane protein 253). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in duodenum adult (RPKM 27.4), large intestine adult (RPKM 19.7) and 4 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tmem253 in Genome Data Viewer
Location:
14; 14 C2
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (52252309..52257244)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (52014852..52019787)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene chaperonin containing Tcp1, subunit 6a (zeta) pseudogene Neighboring gene Rho guanine nucleotide exchange factor (GEF) 40 Neighboring gene predicted gene, 16617 Neighboring gene zinc finger protein 219 Neighboring gene olfactory receptor family 5 subfamily AU member 1 Neighboring gene predicted gene, 22354

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 253
Names
tranmembrane protein 253
transmembrane protein C14orf176 homolog

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033805.3NP_001028977.1  transmembrane protein 253

    See identical proteins and their annotated locations for NP_001028977.1

    Status: VALIDATED

    Source sequence(s)
    AK144313
    Consensus CDS
    CCDS27049.1
    UniProtKB/Swiss-Prot
    Q3UNB8
    Related
    ENSMUSP00000098203.3, ENSMUST00000100638.4
    Conserved Domains (1) summary
    pfam04103
    Location:34113
    CD20; CD20-like family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    52252309..52257244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011245128.3XP_011243430.1  transmembrane protein 253 isoform X1

    See identical proteins and their annotated locations for XP_011243430.1

    UniProtKB/Swiss-Prot
    Q3UNB8
    Conserved Domains (1) summary
    pfam04103
    Location:34113
    CD20; CD20-like family
  2. XM_017316105.3XP_017171594.1  transmembrane protein 253 isoform X1

    UniProtKB/Swiss-Prot
    Q3UNB8
  3. XM_030247905.2XP_030103765.1  transmembrane protein 253 isoform X2

    UniProtKB/TrEMBL
    A0A2I3BR52
    Related
    ENSMUSP00000154460.2, ENSMUST00000227295.2
  4. XM_036158775.1XP_036014668.1  transmembrane protein 253 isoform X1

    UniProtKB/Swiss-Prot
    Q3UNB8