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RPL37 ribosomal protein L37 [ Homo sapiens (human) ]

Gene ID: 6167, updated on 21-Dec-2019

Summary

Official Symbol
RPL37provided by HGNC
Official Full Name
ribosomal protein L37provided by HGNC
Primary source
HGNC:HGNC:10347
See related
Ensembl:ENSG00000145592 MIM:604181
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
L37
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37E family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C2C2-type zinc finger-like motif. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in ovary (RPKM 354.1), bone marrow (RPKM 258.7) and 25 other tissues See more
Orthologs

Genomic context

See RPL37 in Genome Data Viewer
Location:
5p13.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (40825262..40835222, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (40831430..40835387, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene protein kinase AMP-activated catalytic subunit alpha 1 Neighboring gene HNF1 motif-containing MPRA enhancer 12 Neighboring gene CRISPRi-validated cis-regulatory element chr5.1161 Neighboring gene small nucleolar RNA, C/D box 72 Neighboring gene caspase recruitment domain family member 6 Neighboring gene RNA, U7 small nuclear 161 pseudogene Neighboring gene complement C7

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC99572, DKFZp434J0428, DKFZp686G1699

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding TAS
Traceable Author Statement
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
rRNA binding IEA
Inferred from Electronic Annotation
more info
 
structural constituent of ribosome NAS
Non-traceable Author Statement
more info
PubMed 
structural constituent of ribosome TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
SRP-dependent cotranslational protein targeting to membrane TAS
Traceable Author Statement
more info
 
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
Traceable Author Statement
more info
 
translation NAS
Non-traceable Author Statement
more info
PubMed 
translation TAS
Traceable Author Statement
more info
PubMed 
translational initiation TAS
Traceable Author Statement
more info
 
viral transcription TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytosol TAS
Traceable Author Statement
more info
 
cytosolic large ribosomal subunit HDA PubMed 
cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosolic large ribosomal subunit TAS
Traceable Author Statement
more info
PubMed 
synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
60S ribosomal protein L37
Names
60S ribosomal protein L37a
G1.16
large ribosomal subunit protein eL37

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_000997.5NP_000988.1  60S ribosomal protein L37

    See identical proteins and their annotated locations for NP_000988.1

    Status: REVIEWED

    Source sequence(s)
    AC008810
    Consensus CDS
    CCDS3934.1
    UniProtKB/Swiss-Prot
    P61927
    Related
    ENSP00000274242.5, ENST00000274242.10
    Conserved Domains (1) summary
    PTZ00073
    Location:188
    PTZ00073; 60S ribosomal protein L37; Provisional

RNA

  1. NR_159993.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC008810

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    40825262..40835222 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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