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CA12 carbonic anhydrase 12 [ Bos taurus (domestic cattle) ]

Gene ID: 614323, updated on 30-Jan-2025
Official Symbol
CA12provided by VGNC
Official Full Name
carbonic anhydrase 12provided by VGNC
Primary source
VGNC:VGNC:26650
See related
BGD:BT28108; EnsemblRapid:ENSBTAG00070012382
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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See CA12 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 10 NC_037337.1 (46649254..46714597)

Chromosome 10 - NC_037337.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112448547 Neighboring gene uncharacterized LOC112448548 Neighboring gene aph-1 homolog B, gamma-secretase subunit Neighboring gene RAB8B, member RAS oncogene family Neighboring gene ribosomal protein S27 like

Genomic Sequence:
NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables carbonate dehydratase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in one-carbon metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
carbonic anhydrase 12
XP_002690923.1
XP_005211801.1
XP_059746699.1
XP_059746700.1

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RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037337.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    46649254..46714597
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005211744.5 → XP_005211801.1  carbonic anhydrase 12 isoform X2

    See identical proteins and their annotated locations for XP_005211801.1

    UniProtKB/TrEMBL
    A0A3Q1NIM8, F1MPL2
    Related
    ENSBTAP00070017135.1, ENSBTAT00070028129.1
    Conserved Domains (1) summary
    cl00012
    Location:39 → 289
    alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

  2. XM_002690877.7 → XP_002690923.1  carbonic anhydrase 12 isoform X3

    See identical proteins and their annotated locations for XP_002690923.1

    UniProtKB/TrEMBL
    A0A3Q1M0C1, A0A3Q1NIM8
    Related
    ENSBTAP00070017147.1, ENSBTAT00070028142.1
    Conserved Domains (1) summary
    cl00012
    Location:39 → 289
    alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

  3. XM_059890716.1 → XP_059746699.1  carbonic anhydrase 12 isoform X1

  4. XM_059890717.1 → XP_059746700.1  carbonic anhydrase 12 isoform X4

Nucleotide Protein Strain
Heading Accession and Version

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