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HACD2 3-hydroxyacyl-CoA dehydratase 2 [ Bos taurus (domestic cattle) ]

Gene ID: 613886, updated on 5-Sep-2025
Official Symbol
HACD2provided by VGNC
Official Full Name
3-hydroxyacyl-CoA dehydratase 2provided by VGNC
Primary source
VGNC:VGNC:50252
See related
BGD:BT24786
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
PTPLB
Orthologs
all
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See HACD2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 1 NC_037328.1 (67866129..67952692, complement)

Chromosome 1 - NC_037328.1Genomic Context describing neighboring genes Neighboring gene adenylate cyclase 5 Neighboring gene basic salivary proline-rich protein 2-like Neighboring gene histone H4-like Neighboring gene myosin light chain kinase Neighboring gene large ribosomal subunit protein eL21-like

Genomic Sequence:
NC_037328.1 Chromosome 1 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Dominette sequence data
  • BioProject: PRJNA294306
  • Analysis date: Tue Dec 17 08:57:05 2024

Related articles in PubMed

  1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3-hydroxyacyl-CoA dehydratase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingolipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in very long-chain fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2
Names
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
protein-tyrosine phosphatase-like member B
very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2
NP_001124229.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130757.2 → NP_001124229.1  very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2

    See identical proteins and their annotated locations for NP_001124229.1

    Status: PROVISIONAL

    Source sequence(s)
    BC112557
    UniProtKB/Swiss-Prot
    Q2KIP8
    Conserved Domains (1) summary
    pfam04387
    Location:85 → 244
    PTPLA; Protein tyrosine phosphatase-like protein, PTPLA

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037328.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    67866129..67952692 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2KIP8.2 GenPept UniProtKB/Swiss-Prot:Q2KIP8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials