POLE4 DNA polymerase epsilon 4, accessory subunit [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: POLE4provided by VGNC
Official Full Name: DNA polymerase epsilon 4, accessory subunitprovided by VGNC
Primary source: VGNC:VGNC:33121
See related: BGD:BT21508; Ensembl:ENSBTAG00000062291
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	11	NC_037338.1 (9706386..9717914, complement)

Chromosome 11 - NC_037338.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of epsilon DNA polymerase complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: DNA polymerase epsilon subunit 4

Names: DNA polymerase II subunit 4; DNA-directed DNA polymerase epsilon 4; polymerase (DNA-directed), epsilon 4 (p12 subunit); polymerase (DNA-directed), epsilon 4, accessory subunit

NP_001094695.1

EC 2.7.7.7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001101225.2 → NP_001094695.1 DNA polymerase epsilon subunit 4

See identical proteins and their annotated locations for NP_001094695.1

Status: PROVISIONAL

Source sequence(s)

BC149592

UniProtKB/Swiss-Prot

A6QQ14

Related

ENSBTAP00000103747.1, ENSBTAT00000097410.1

Conserved Domains (1) summary

cl23735
Location:39 → 102

H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...