LTB4R leukotriene B4 receptor [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: LTB4Rprovided by VGNC
Official Full Name: leukotriene B4 receptorprovided by VGNC
Primary source: VGNC:VGNC:31069
See related: BGD:BT11704; EnsemblRapid:ENSBTAG00070036316
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	10	NC_037337.1 (20853775..20855801, complement)

Chromosome 10 - NC_037337.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037337.1 Chromosome 10 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

In luteal-phase endometrium, expression of 5-LO (5-lipoxygenase) and LTB4R (leukotriene B4 receptor) is highest on Days 2-4; expression of LTCS (leukotriene-C4 synthase) and CysLTR2 (cysteinyl leukotriene receptor 2) is highest on Days 16-18. In luteal-phase endometrium, LTB4 level is highest on Days 2-4; LTC4 level is highest on Days 16-18. Studies were conducted in Poland on Holstein Polish Black and White dairy cows.
Title: Leukotriene production profiles and actions in the bovine endometrium during the oestrous cycle.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables complement component C5a receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables leukotriene receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in complement receptor mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cytosolic calcium ion concentration	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: leukotriene B4 receptor 1

Names: LTB4-R 1; LTB4-R1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001034738.1 → NP_001029910.1 leukotriene B4 receptor 1

See identical proteins and their annotated locations for NP_001029910.1

Status: PROVISIONAL

Source sequence(s)

BC102075

UniProtKB/Swiss-Prot

Q3T181

UniProtKB/TrEMBL

A0AAA9SR24

Related

ENSBTAP00070049350.1, ENSBTAT00070081395.1

Conserved Domains (2) summary

cd14964
Location:21 → 45

7tm_GPCRs; TM helix 1 [structural motif]

cl28897
Location:19 → 298

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily