CALCR calcitonin receptor [Bos taurus (domestic cattle)] - Gene

Summary

Official Symbol: CALCRprovided by VGNC
Official Full Name: calcitonin receptorprovided by VGNC
Primary source: VGNC:VGNC:26704
See related: BGD:BT11893; EnsemblRapid:ENSBTAG00070001218
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_12	current	ARS-UCD2.0 (GCF_002263795.3)	4	NC_037331.1 (10781951..10893236, complement)

Chromosome 4 - NC_037331.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037331.1 Chromosome 4 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Dominette sequence data
BioProject: PRJNA294306
Analysis date: Tue Dec 17 08:57:05 2024

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

expressed in preimplantation embryos
Title: The effects of calcitonin on the development of and Ca2+ levels in heat-shocked bovine preimplantation embryos in vitro.

Submit: New GeneRIF Correction

General gene information

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Markers

BMS1788 (e-PCR), detects polymorphism
- UniSTS:9797

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables amylin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables calcitonin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell surface receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cytosolic calcium ion concentration	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in axon	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: calcitonin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001076269.2 → NP_001069737.2 calcitonin receptor

Status: VALIDATED

Source sequence(s)

BC114123

UniProtKB/TrEMBL

A0A3Q1LPY9

Related

ENSBTAP00070001614.1, ENSBTAT00070002781.1

Conserved Domains (2) summary

pfam00002
Location:166 → 407

7tm_2; 7 transmembrane receptor (Secretin family)

pfam02793
Location:90 → 158

HRM; Hormone receptor domain