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CTXN3 cortexin 3 [ Homo sapiens (human) ]

Gene ID: 613212, updated on 5-Jan-2022

Summary

Official Symbol
CTXN3provided by HGNC
Official Full Name
cortexin 3provided by HGNC
Primary source
HGNC:HGNC:31110
See related
Ensembl:ENSG00000205279 MIM:618746
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KABE
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Nov 2021]
Expression
Restricted expression toward kidney (RPKM 21.3) See more
Orthologs
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Genomic context

See CTXN3 in Genome Data Viewer
Location:
5q23.2
Exon count:
4
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (127649082..127658630)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (126984774..126994322)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein K pseudogene 1 Neighboring gene proline rich coiled-coil 1 Neighboring gene uncharacterized LOC105379164 Neighboring gene coiled-coil domain containing 192 Neighboring gene cullin 1 pseudogene 1 Neighboring gene SLC12A2 divergent transcript Neighboring gene uncharacterized LOC101929964

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly.
GeneReviews: Not available
A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cortexin-3
Names
kidney and brain-expressed protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001048252.3NP_001041717.1  cortexin-3

    See identical proteins and their annotated locations for NP_001041717.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) utilizes an alternate first exon. Transcript variants 1 and 2 encode the same protein.
    Source sequence(s)
    AB219764
    Consensus CDS
    CCDS34221.1
    UniProtKB/Swiss-Prot
    Q4LDR2
    Related
    ENSP00000368758.3, ENST00000379445.8
    Conserved Domains (1) summary
    pfam11057
    Location:981
    Cortexin; Cortexin of kidney
  2. NM_001127385.2NP_001120857.1  cortexin-3

    See identical proteins and their annotated locations for NP_001120857.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) utilizes an alternate first exon. Transcript variants 1 and 2 encode the same protein.
    Source sequence(s)
    AB219832
    Consensus CDS
    CCDS34221.1
    UniProtKB/Swiss-Prot
    Q4LDR2
    Related
    ENSP00000378732.3, ENST00000395322.3
    Conserved Domains (1) summary
    pfam11057
    Location:981
    Cortexin; Cortexin of kidney

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    127649082..127658630
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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