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BRCC3 BRCA1/BRCA2-containing complex subunit 3 [ Canis lupus familiaris (dog) ]

Gene ID: 612642, updated on 5-Mar-2024

Summary

Gene symbol
BRCC3
Gene description
BRCA1/BRCA2-containing complex subunit 3
See related
Ensembl:ENSCAFG00845030300
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: X
Exon count:
12
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) X NC_051843.1 (126208828..126271057)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) X NC_006621.4 (108074648..108136853)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) X NC_049260.1 (124199851..124262068)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) X NC_049299.1 (121956711..122018913)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) X NC_049780.1 (124479132..124541327)

Chromosome X - NC_051843.1Genomic Context describing neighboring genes Neighboring gene FUN14 domain containing 2 Neighboring gene mature T cell proliferation 1 Neighboring gene C-X9-C motif containing 4 Neighboring gene small nuclear ribonucleoprotein-associated protein B'-like Neighboring gene phosphatidylinositol-binding clathrin assembly protein-like

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of BRCA1-A complex IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of BRISC complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
lys-63-specific deubiquitinase BRCC36
XP_003640289.1
XP_005642104.1
XP_022271387.1
XP_022271388.1
XP_022271389.1
XP_038307241.1
XP_038307242.1
XP_038307243.1
XP_038307244.1
XP_038307245.1
XP_038307246.1
XP_038307247.1
XP_038320526.1
XP_038380709.1
XP_038380710.1
XP_038380711.1
XP_038380712.1
XP_038380713.1
XP_038380714.1
XP_038380715.1
XP_038444673.1
XP_038444674.1
XP_038444675.1
XP_038444676.1
XP_038444677.1
XP_038444678.1
XP_038444679.1
XP_038509192.1
XP_038509193.1
XP_038509194.1
XP_038509196.1
XP_038509197.1
XP_038509198.1
XP_038509199.1
XP_855467.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051843.1 Reference ROS_Cfam_1.0

    Range
    126208828..126271057
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038451313.1XP_038307241.1  lys-63-specific deubiquitinase BRCC36 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXT8, A0A8I3QJH2, A0A8P0NQ87
    Related
    ENSCAFP00845042289.1, ENSCAFT00845053807.1
    Conserved Domains (1) summary
    cd08068
    Location:9292
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  2. XM_038451319.1XP_038307247.1  lys-63-specific deubiquitinase BRCC36 isoform X7

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:9266
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  3. XM_038451316.1XP_038307244.1  lys-63-specific deubiquitinase BRCC36 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QXT8, A0A8C0TEH4, A0A8I3Q664
    Related
    ENSCAFP00845042275.1, ENSCAFT00845053789.1
    Conserved Domains (1) summary
    cd08068
    Location:9267
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  4. XM_038451314.1XP_038307242.1  lys-63-specific deubiquitinase BRCC36 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:9279
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  5. XM_038451318.1XP_038307246.1  lys-63-specific deubiquitinase BRCC36 isoform X6

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:9254
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  6. XM_038451315.1XP_038307243.1  lys-63-specific deubiquitinase BRCC36 isoform X3

    UniProtKB/TrEMBL
    A0A8C0TDN7
    Conserved Domains (1) summary
    cd08068
    Location:9268
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  7. XM_038451317.1XP_038307245.1  lys-63-specific deubiquitinase BRCC36 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:36267
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049299.1 Alternate UMICH_Zoey_3.1

    Range
    121956711..122018913
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038524781.1XP_038380709.1  lys-63-specific deubiquitinase BRCC36 isoform X1

    Conserved Domains (1) summary
    cd08068
    Location:9292
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  2. XM_038524787.1XP_038380715.1  lys-63-specific deubiquitinase BRCC36 isoform X7

    Conserved Domains (1) summary
    cd08068
    Location:9266
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  3. XM_038524784.1XP_038380712.1  lys-63-specific deubiquitinase BRCC36 isoform X4

    Conserved Domains (1) summary
    cd08068
    Location:9267
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  4. XM_038524782.1XP_038380710.1  lys-63-specific deubiquitinase BRCC36 isoform X2

    Conserved Domains (1) summary
    cd08068
    Location:9279
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  5. XM_038524786.1XP_038380714.1  lys-63-specific deubiquitinase BRCC36 isoform X6

    Conserved Domains (1) summary
    cd08068
    Location:9254
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  6. XM_038524783.1XP_038380711.1  lys-63-specific deubiquitinase BRCC36 isoform X3

    Conserved Domains (1) summary
    cd08068
    Location:9268
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  7. XM_038524785.1XP_038380713.1  lys-63-specific deubiquitinase BRCC36 isoform X5

    Conserved Domains (1) summary
    cd08068
    Location:36267
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049780.1 Alternate UNSW_CanFamBas_1.0

    Range
    124479132..124541327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038653264.1XP_038509192.1  lys-63-specific deubiquitinase BRCC36 isoform X1

    Conserved Domains (1) summary
    cd08068
    Location:9292
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  2. XM_038653271.1XP_038509199.1  lys-63-specific deubiquitinase BRCC36 isoform X7

    Conserved Domains (1) summary
    cd08068
    Location:9266
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  3. XM_038653268.1XP_038509196.1  lys-63-specific deubiquitinase BRCC36 isoform X4

    Conserved Domains (1) summary
    cd08068
    Location:9267
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  4. XM_038653265.1XP_038509193.1  lys-63-specific deubiquitinase BRCC36 isoform X2

    Conserved Domains (1) summary
    cd08068
    Location:9279
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  5. XM_038653270.1XP_038509198.1  lys-63-specific deubiquitinase BRCC36 isoform X6

    Conserved Domains (1) summary
    cd08068
    Location:9254
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  6. XM_038653266.1XP_038509194.1  lys-63-specific deubiquitinase BRCC36 isoform X3

    Conserved Domains (1) summary
    cd08068
    Location:9268
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  7. XM_038653269.1XP_038509197.1  lys-63-specific deubiquitinase BRCC36 isoform X5

    Conserved Domains (1) summary
    cd08068
    Location:36267
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049260.1 Alternate UU_Cfam_GSD_1.0

    Range
    124199851..124262068
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038588745.1XP_038444673.1  lys-63-specific deubiquitinase BRCC36 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXT8, A0A8I3QJH2, A0A8P0NQ87
    Conserved Domains (1) summary
    cd08068
    Location:9292
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  2. XM_038588751.1XP_038444679.1  lys-63-specific deubiquitinase BRCC36 isoform X7

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:9266
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  3. XM_038588748.1XP_038444676.1  lys-63-specific deubiquitinase BRCC36 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QXT8, A0A8C0TEH4, A0A8I3Q664
    Conserved Domains (1) summary
    cd08068
    Location:9267
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  4. XM_038588746.1XP_038444674.1  lys-63-specific deubiquitinase BRCC36 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:9279
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  5. XM_038588750.1XP_038444678.1  lys-63-specific deubiquitinase BRCC36 isoform X6

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:9254
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  6. XM_038588747.1XP_038444675.1  lys-63-specific deubiquitinase BRCC36 isoform X3

    UniProtKB/TrEMBL
    A0A8C0TDN7
    Conserved Domains (1) summary
    cd08068
    Location:9268
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  7. XM_038588749.1XP_038444677.1  lys-63-specific deubiquitinase BRCC36 isoform X5

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:36267
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006621.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    108074648..108136853
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_850374.7XP_855467.3  lys-63-specific deubiquitinase BRCC36 isoform X1

    UniProtKB/TrEMBL
    A0A8C0QXT8, A0A8I3QJH2, A0A8P0NQ87
    Conserved Domains (1) summary
    cd08068
    Location:9292
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  2. XM_038464598.1XP_038320526.1  lys-63-specific deubiquitinase BRCC36 isoform X7

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:9266
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  3. XM_003640241.5XP_003640289.1  lys-63-specific deubiquitinase BRCC36 isoform X4

    UniProtKB/TrEMBL
    A0A8C0QXT8, A0A8C0TEH4, A0A8I3Q664
    Conserved Domains (1) summary
    cd08068
    Location:9267
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  4. XM_022415679.2XP_022271387.1  lys-63-specific deubiquitinase BRCC36 isoform X2

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:9279
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  5. XM_022415681.2XP_022271389.1  lys-63-specific deubiquitinase BRCC36 isoform X6

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:9254
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  6. XM_022415680.2XP_022271388.1  lys-63-specific deubiquitinase BRCC36 isoform X3

    UniProtKB/TrEMBL
    A0A8C0TDN7
    Conserved Domains (1) summary
    cd08068
    Location:9268
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex
  7. XM_005642047.4XP_005642104.1  lys-63-specific deubiquitinase BRCC36 isoform X5

    See identical proteins and their annotated locations for XP_005642104.1

    UniProtKB/TrEMBL
    A0A8C0QXT8
    Conserved Domains (1) summary
    cd08068
    Location:36267
    MPN_BRCC36; Mov34/MPN/PAD-1 family: BRCC36, a subunit of BRCA1-A complex