MARCHF1 membrane associated ring-CH-type finger 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: MARCHF1provided by VGNC
Official Full Name: membrane associated ring-CH-type finger 1provided by VGNC
Primary source: VGNC:VGNC:43014
See related: Ensembl:ENSCAFG00845006581 RGD:12404650
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as: MARCH1
Orthologs: all
: Try the new Gene page
Try the new Transcripts and proteins table

Genomic context

Location:: chromosome: 15

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	15	NC_051819.1 (60512737..61307283, complement)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	15	NC_006597.4 (60118313..60912318, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	15	NC_049236.1 (60206169..61004664, complement)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	15	NC_049275.1 (59745776..60561370, complement)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	15	NC_049756.1 (59837018..60638108, complement)

Chromosome 15 - NC_051819.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables MHC protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in antigen processing and presentation of peptide antigen via MHC class II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein polyubiquitination	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in early endosome membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in lysosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: E3 ubiquitin-protein ligase MARCHF1

XP_022259274.1

EC 2.3.2.27

XP_038308003.1

EC 2.3.2.27

XP_038308004.1

EC 2.3.2.27

XP_038308005.1

EC 2.3.2.27

XP_038308006.1

EC 2.3.2.27

XP_038352668.1

EC 2.3.2.27

XP_038352669.1

EC 2.3.2.27

XP_038352670.1

EC 2.3.2.27

XP_038352671.1

EC 2.3.2.27

XP_038352672.1

EC 2.3.2.27

XP_038415067.1

EC 2.3.2.27

XP_038415068.1

EC 2.3.2.27

XP_038479010.1

EC 2.3.2.27

XP_038479011.1

EC 2.3.2.27

XP_038479012.1

EC 2.3.2.27

XP_038479013.1

EC 2.3.2.27

XP_038479014.1

EC 2.3.2.27

XP_038544682.1

EC 2.3.2.27

XP_038544683.1

EC 2.3.2.27

XP_038544684.1

EC 2.3.2.27

XP_038544685.1

EC 2.3.2.27

XP_038544686.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051819.1 Reference ROS_Cfam_1.0

Range

60512737..61307283 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038688754.1 → XP_038544682.1 E3 ubiquitin-protein ligase MARCHF1 isoform X1

UniProtKB/TrEMBL

A0A8C0QVN5, A0A8I3N392

Related

ENSCAFP00845009127.1, ENSCAFT00845011691.1

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038688757.1 → XP_038544685.1 E3 ubiquitin-protein ligase MARCHF1 isoform X4

UniProtKB/TrEMBL

A0A8C0JXS9, A0A8I3RUV6

Related

ENSCAFP00845009140.1, ENSCAFT00845011706.1

Conserved Domains (1) summary

cd16698
Location:79 → 130

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038688758.1 → XP_038544686.1 E3 ubiquitin-protein ligase MARCHF1 isoform X5

Conserved Domains (1) summary

cd16698
Location:33 → 82

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038688755.1 → XP_038544683.1 E3 ubiquitin-protein ligase MARCHF1 isoform X2

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038688756.1 → XP_038544684.1 E3 ubiquitin-protein ligase MARCHF1 isoform X3

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

Alternate UMICH_Zoey_3.1

Genomic

NC_049275.1 Alternate UMICH_Zoey_3.1

Range

59745776..60561370 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038496740.1 → XP_038352668.1

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038496743.1 → XP_038352671.1

Conserved Domains (1) summary

cd16698
Location:79 → 130

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038496744.1 → XP_038352672.1
XM_038496741.1 → XP_038352669.1

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038496742.1 → XP_038352670.1

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049756.1 Alternate UNSW_CanFamBas_1.0

Range

59837018..60638108 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038623082.1 → XP_038479010.1

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038623085.1 → XP_038479013.1

Conserved Domains (1) summary

cd16698
Location:79 → 130

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038623086.1 → XP_038479014.1
XM_038623083.1 → XP_038479011.1

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038623084.1 → XP_038479012.1

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049236.1 Alternate UU_Cfam_GSD_1.0

Range

60206169..61004664 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038559139.1 → XP_038415067.1 E3 ubiquitin-protein ligase MARCHF1 isoform X4

UniProtKB/TrEMBL

A0A8C0JXS9, A0A8I3RUV6

Conserved Domains (1) summary

cd16698
Location:79 → 130

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038559140.1 → XP_038415068.1 E3 ubiquitin-protein ligase MARCHF1 isoform X5

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006597.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

60118313..60912318 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038452075.1 → XP_038308003.1 E3 ubiquitin-protein ligase MARCHF1 isoform X1

UniProtKB/TrEMBL

A0A8C0QVN5, A0A8I3N392

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038452078.1 → XP_038308006.1 E3 ubiquitin-protein ligase MARCHF1 isoform X4

UniProtKB/TrEMBL

A0A8C0JXS9, A0A8I3RUV6

Conserved Domains (1) summary

cd16698
Location:79 → 130

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_022403566.2 → XP_022259274.1 E3 ubiquitin-protein ligase MARCHF1 isoform X5

Conserved Domains (1) summary

cd16698
Location:33 → 82

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038452076.1 → XP_038308004.1 E3 ubiquitin-protein ligase MARCHF1 isoform X2

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins
XM_038452077.1 → XP_038308005.1 E3 ubiquitin-protein ligase MARCHF1 isoform X3

Conserved Domains (1) summary

cd16698
Location:332 → 383

RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins