U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TNFSF8 TNF superfamily member 8 [ Canis lupus familiaris (dog) ]

Gene ID: 612608, updated on 25-Jul-2026
Official Symbol
TNFSF8provided by VGNC
Official Full Name
TNF superfamily member 8provided by VGNC
Primary source
VGNC:VGNC:47673
See related
Ensembl:ENSCAFG00845010341 RGD:12287755
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Also known as
TNLG3A
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See TNFSF8 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
4
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 11 NC_051815.1 (70104816..70130774, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 11 NC_006593.4 (67382605..67408573, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 11 NC_049232.1 (69390910..69416891, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 11 NC_049271.1 (68618787..68644979, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 11 NC_049752.1 (68659603..68685784, complement)

Chromosome 11 - NC_051815.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106559509 Neighboring gene TNF superfamily member 15 Neighboring gene uncharacterized LOC111097961 Neighboring gene tenascin C Neighboring gene uncharacterized LOC119874050

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Comparative genomic analysis of eutherian tumor necrosis factor ligand genes. Premzl M. Immunogenetics, 2016 Feb. PMID 26646413
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in CD8-positive, alpha-beta T cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
tumor necrosis factor ligand superfamily member 8
Names
tumor necrosis factor ligand 3A
tumor necrosis factor superfamily member 8

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051815.1 Reference ROS_Cfam_1.0

    Range
    70104816..70130774 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038682554.1 → XP_038538482.1  tumor necrosis factor ligand superfamily member 8

    UniProtKB/TrEMBL
    A0A0U5J532, A0A8C0JL12, E2R8I1
    Related
    ENSCAFP00845014191.1, ENSCAFT00845018201.1
    Conserved Domains (1) summary
    pfam00229
    Location:113 → 230
    TNF; TNF(tumor Necrosis Factor) family

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049271.1 Alternate UMICH_Zoey_3.1

    Range
    68618787..68644979 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038491085.1 → XP_038347013.1  

    Conserved Domains (1) summary
    pfam00229
    Location:113 → 230
    TNF; TNF(tumor Necrosis Factor) family

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049752.1 Alternate UNSW_CanFamBas_1.0

    Range
    68659603..68685784 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038617097.1 → XP_038473025.1  

    Conserved Domains (1) summary
    pfam00229
    Location:113 → 230
    TNF; TNF(tumor Necrosis Factor) family

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049232.1 Alternate UU_Cfam_GSD_1.0

    Range
    69390910..69416891 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038553222.1 → XP_038409150.1  tumor necrosis factor ligand superfamily member 8

    UniProtKB/TrEMBL
    A0A0U5J532, A0A8C0JL12, E2R8I1
    Conserved Domains (1) summary
    pfam00229
    Location:113 → 230
    TNF; TNF(tumor Necrosis Factor) family

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006593.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    67382605..67408573 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_850342.5 → XP_855435.1  tumor necrosis factor ligand superfamily member 8

    UniProtKB/TrEMBL
    A0A0U5J532, A0A8C0JL12, E2R8I1
    Conserved Domains (1) summary
    pfam00229
    Location:113 → 230
    TNF; TNF(tumor Necrosis Factor) family
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.