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INSC INSC spindle orientation adaptor protein [ Canis lupus familiaris (dog) ]

Gene ID: 611775, updated on 25-Jul-2026
Official Symbol
INSCprovided by VGNC
Official Full Name
INSC spindle orientation adaptor proteinprovided by VGNC
Primary source
VGNC:VGNC:42038
See related
Ensembl:ENSCAFG00845023608 RGD:12401984
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
all
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See INSC in Genome Data Viewer
Location:
chromosome: 21
Exon count:
14
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 21 NC_051825.1 (39072642..39160340)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 21 NC_006603.4 (37447110..37565970)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 21 NC_049242.1 (38551635..38670419)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 21 NC_049281.1 (38058728..38177862)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 21 NC_049762.1 (38263829..38382671)

Chromosome 21 - NC_051825.1Genomic Context describing neighboring genes Neighboring gene calcitonin receptor-stimulating peptide-2 Neighboring gene calcitonin related polypeptide alpha Neighboring gene uncharacterized LOC111091612 Neighboring gene uncharacterized LOC111091566

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytoskeletal adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apical protein localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in asymmetric cell division IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of mitotic spindle orientation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of asymmetric cell division IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in apical cortex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
protein inscuteable homolog
Names
inscuteable homolog

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051825.1 Reference ROS_Cfam_1.0

    Range
    39072642..39160340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038430598.1 → XP_038286526.1  protein inscuteable homolog

    UniProtKB/TrEMBL
    A0A8I3PFE8, A0A8I3PFS5
    Related
    ENSCAFP00845032851.1, ENSCAFT00845041883.1
    Conserved Domains (1) summary
    pfam16748
    Location:23 → 66
    INSC_LBD; Inscuteable LGN-binding domain

RNA

  1. XR_005298826.1 RNA Sequence

  2. XR_005298827.1 RNA Sequence

  3. XR_005298828.1 RNA Sequence

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049281.1 Alternate UMICH_Zoey_3.1

    Range
    38058728..38177862
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038505902.1 → XP_038361830.1  

    Conserved Domains (1) summary
    pfam16748
    Location:23 → 66
    INSC_LBD; Inscuteable LGN-binding domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049762.1 Alternate UNSW_CanFamBas_1.0

    Range
    38263829..38382671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038633307.1 → XP_038489235.1  

    Conserved Domains (1) summary
    pfam16748
    Location:23 → 66
    INSC_LBD; Inscuteable LGN-binding domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049242.1 Alternate UU_Cfam_GSD_1.0

    Range
    38551635..38670419
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038569125.1 → XP_038425053.1  protein inscuteable homolog

    UniProtKB/TrEMBL
    A0A8I3PFE8, A0A8I3PFS5
    Conserved Domains (1) summary
    pfam16748
    Location:23 → 66
    INSC_LBD; Inscuteable LGN-binding domain

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006603.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    37447110..37565970
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038456484.1 → XP_038312412.1  protein inscuteable homolog

    UniProtKB/TrEMBL
    A0A8I3PFE8, A0A8I3PFS5
    Conserved Domains (1) summary
    pfam16748
    Location:23 → 66
    INSC_LBD; Inscuteable LGN-binding domain
Nucleotide Protein
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